P Aeruginosa Research Paper

P. aeruginosa is an opportunistic bacterium that causes different conditions such as septicemia, pneumonia, urinary tract infection (UTI), endocarditis, and skin-eye-ear infections [1]. This bacterium is one of the major causes of hospitalized infections and the main cause of death in patients with cystic fibrosis, severe burns, and AIDS [2]. P. aeruginosa is one global threat of hospitalized infections in the entire world [3]. It is described that about 63,000 people in the U.S. and 25,000 in the E.U. die each year because of the infectious diseases caused by multi-drug resistant (MDR) bacteria [4]. MBLs are the genes causing resistance in P. aeruginosa. The MBL-encoding genes, blaIMP and blaVIM, which are often located on integrons, can easily
spread between bacteria [5]. Both genes of imp and vim-type in P. aeruginosa clinical strains are often located on class 1 integrons [6]. The integrons are motionless per se, yet as they are located on transposons or plasmids, they would be mobile and thus can spread the