ecological/environmental current legislation future legislation international legislation regulatory bodies and processes government policies government term and change trading policies funding, grants and initiatives home market pressure- groups international pressure- groups wars and conflicts
Political
1. No significant awareness program around disease education/recognition resulting in lower awareness in policy makers.
2. Orphan disease.
3. Patient demographics (Only effects people of certain ethnicity).
4. HSCT is controversial (??).
Economical
1. Funding for HLA matching expense. (Not covered for both parties).
2. Relatively high number of uninsured patients (~18%).
3. Patient caregiver needs lot of time off Severity of the disease.
4. High non-medical costs.
criteria examples home economy economy trends overseas economies general taxation taxation specific to product/services seasonality issues market/trade cycles specific industry factors market routes trends distribution trends customer/end-user drivers interest/ exchange rates international trade and monetary issues
criteria examples lifestyle trends demographics consumer attitudes and opinions media views law changes affecting social factors brand, company, technology image consumer buying patterns fashion and role models major events and influences buying access and trends ethnic/religious factors advertising and publicity ethical issues
Social
1. Parents availability for transplant
2. Acute Care Vs Chronic care alternatives
3. Parents refusal
4. Patients education w.r.to Severity of the disease
5. Not many big campigns/ celebrity endorsement.
6. Post grafting complications.
7. Physicians (GP ) awareness
Technological
1. FDA clearance
2. Not enough technology for better forecasting the severity of disease
3. Can’t predict risks due