Phage Therapy: Effective Use Of Bacteriophage Treatment

Bacteriophage is a term that means bacteria eater, it describes the agent’s ability to kill bacteria. Bacteriophages can infect and create more copies of itself inside of a bacterial host which is why they are considered pathogenic phages (Jassim et al, 2014). Overall, Bacteriophages are one of the most ordinary and unique organisms in the global sum of all ecosystems that can be used to make the world a healthier place to sustain human life. In today's society the overuse of antibiotics in the agriculture industry has caused very strong antibiotic resistant bacteria (Page and Gautier 2012). Because antibiotics are not doing a good job at containing these bacterias like they use to, scientist are now moving towards bacteriophages.
Phage therapy is a method that is very effective. Phage therapy consist of the intended bacteriophages that can infect and kill specific bacteria. (Sulakvelidze 2016) Bacteriophages destroy those bacterias, and then release virions. Virions can expand the cycle by moving to other places in the body where there is infection. (Sulakvelidze 2016). Which is a reason why phage therapy may be a more effective treatment. Antibiotics tend to have a larger focused as an attempt to kill nearly every bacteria, even good bacteria, while bacteriophages specifically cater to certain types of bacteria, killing their host, and then migrating to find more of that same bacteria causing an
The patients were split into two groups. 223 patients were in group 1 that received Staphylococcus aureus phages, and 117 patients were in group 2 that received antibiotics. In addition, 48 patients that were in group 1 received phages by i.v. injection. The results showed that there was no side effects in any of the patients. Moreover, recovery was evaluated in 82% of the patients in the group that received phages. In comparison, only 64% of the patients in the antibiotic treated group recovered completely.The percent recovery in the group receiving phages by i.v injection was even higher at 95%, which was higher than all 223 phage-treated patients (Meladze G D 2016). Overall, this study shows that Staphylococcus aureus bacteriophages were 18% more effective than antibiotics when treating diseases in the lungs and pleura. This is mainly because at the spot of infection bacteriophages were able to make more copies of itself rapidly to get rid of the infection. Antibiotics, on the other hand, do not necessarily concentrate at the site of infection.This could a reason why the recovery percentage was much higher for those receiving phages rather than those who received antibiotics. Another advantage of using bacteriophages instead of antibiotics is that bacteriophages are phages that can be found throughout nature(BTER). This means that it is not difficult to find new bacteriophages