Pharmacology Review Sheet
WEEK 1 GEN
Adverse reactions for drugs occur because:
No drug has only one receptor it binds to.
A drug that occupies and "turns on" a receptor is an: agonist Before marketing a new drug, the drug company asks the FDA to approve its choice of: trade name
The time between when a drug response is observable and when there is no longer an observable drug effect is called the duration of action
This term refers to how much of a drug must be given to see a desired response potency Nicotine induces P-450 enzymes in the liver. An AIDS patient taking a protease inhibitor drug which is metabolized by these enzymes would experience which of the following if they smoked
Lower blood levels of the protease inhibitor
Drug A can produce the same effects as Drug B at a lower dose of drug A. Drug A is: more potent than Drug B.
Which of the following recent advances is most likely to influence future drug development and use
Our knowledge of genetic differences between people
You have a patient with Parkinson's disease, and you want to get more dopamine into the brain. Dopamine is a polar molecule. How can you accomplish this best?
Give a lipid soluble precursor to dopamine which can convert in the brain
Most drug work by
Binding to a specific receptor on the cell
A drug that occupies a receptor but does not activate the receptor is a antagonist The time between when a drug is administered and when there are observable effects is called the onset of action
Adverse reactions to drugs occur because
No drug has only one receptor it binds to
Once a drug's peak effect has been reached, further doses of the drug will increase efficacy false WEEK 2 GEN
After a drug is administered, it must get to the site where it exerts its action. This phase of pharmacokinetics is called distribution Which pregnancy category indicates that animal studies and clinical trials show a significant risk to the mother and/or fetus that clearly
Adverse reactions for drugs occur because:
No drug has only one receptor it binds to.
A drug that occupies and "turns on" a receptor is an: agonist Before marketing a new drug, the drug company asks the FDA to approve its choice of: trade name
The time between when a drug response is observable and when there is no longer an observable drug effect is called the duration of action
This term refers to how much of a drug must be given to see a desired response potency Nicotine induces P-450 enzymes in the liver. An AIDS patient taking a protease inhibitor drug which is metabolized by these enzymes would experience which of the following if they smoked
Lower blood levels of the protease inhibitor
Drug A can produce the same effects as Drug B at a lower dose of drug A. Drug A is: more potent than Drug B.
Which of the following recent advances is most likely to influence future drug development and use
Our knowledge of genetic differences between people
You have a patient with Parkinson's disease, and you want to get more dopamine into the brain. Dopamine is a polar molecule. How can you accomplish this best?
Give a lipid soluble precursor to dopamine which can convert in the brain
Most drug work by
Binding to a specific receptor on the cell
A drug that occupies a receptor but does not activate the receptor is a antagonist The time between when a drug is administered and when there are observable effects is called the onset of action
Adverse reactions to drugs occur because
No drug has only one receptor it binds to
Once a drug's peak effect has been reached, further doses of the drug will increase efficacy false WEEK 2 GEN
After a drug is administered, it must get to the site where it exerts its action. This phase of pharmacokinetics is called distribution Which pregnancy category indicates that animal studies and clinical trials show a significant risk to the mother and/or fetus that clearly