Review Sheet
Exercise 4
Endocrine System Physiology
Name Laura Bauer
Lab Time/Date Thursday 5:30-7:30
Activity 1 Metabolism and Thyroid Hormone
Part 1
1 Which rat had the fastest basal metabolic rate (BMR)?
The Normal rat had the fastest BMR.
2 Why did the metabolic rates differ between the normal rat and the surgically altered rats? How well did the results compare with your prediction? ___
The BMRs differed because the surgically altered rats were missing either the Pituitary or Thryoid gland that release thyroid hormones.
3 If an animal has been thyroidectomized, what hormone(s) would be missing in its blood?
The animal will be missing trioodythronine and thyroxine.
4 If an animal has been hypophysectomized, what effect would you expect to see in the hormone levels in its body?
Due to the rat's missing pituitary gland, TSH will be missing.
Part 2
5 What was the effect of thyroxine injections on the normal rat’s BMR? ___
The normal rat's BMR increased with thyroxine injections.
6 What was the effect of thyroxine injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of thyroxine in the syringe too large, too small, or just right? ___
The BMR of the thyroidectomized rat increased but was still not as high was the normal rat's. The dose was too low.
7 What was the effect of thyroxine injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of thyroxine in the syringe too large, too small, or just right?
The BMR of the hypophysectomized rat also increased but was not as high as the normal rat's. The dose was too low.
Part 3
8 What was the effect of thyroid-stimulating hormone (TSH) injections on the normal rat’s BMR? ___
It increased the rat's BMR.
9 What was the effect of TSH injections on the thyroidectomized rat’s BMR? How does