Pododylox Case Study
Podofilox
In a nonpregnant patient, podofilox gel or solution is the authors’ first choice. This antimitotic agent is either chemically synthesized or purified from naturally occurring podophyllin resin. Podofilox is used in the treatment of external genital warts or condyloma acuminatum. It is applied twice daily for 3 consecutive days and repeated for up to 4 weeks. Application stimulates visible necrosis of wart tissue. Side effects are minimal.
To ensure that the patient is fully aware of the correct method of therapy and to identify which specific warts should be treated, the prescriber should demonstrate the technique for initial application of the medication. No more than 0.5 g of gel per day should be used. Limit the total wart tissue …show more content…
It is a physician-applied medicine used in the treatment of external genital warts and condyloma acuminatum. It can be applied weekly for up to 6 weeks. Warts visible after 6 treatments usually do not respond to further therapy.
Podophyllin is applied directly to warts, but no more than 0.5 mL should be used with 1 treatment. Before application, thoroughly cleanse the affected area. Avoid contact with healthy tissue. Apply the medicine sparingly, and allow it to dry thoroughly. The initial application should be for 30-40 minutes; subsequent applications can be for 1-4 hours. Remove dried podophyllin with alcohol or with soap and water. Do not treat large areas or numerous warts at once.
Ulceration and pain are potential side effects of podophyllin therapy. In addition, special care must be taken in using this agent because it not only causes tissue injury but also can be absorbed systemically and cause neurologic toxicity. Deaths have occurred with the use of podophyllin on exuberant perianal warts; the surface area of the lesions increases the absorption of the drug. Podophyllin is contraindicated in pregnancy.
The authors prefer podofilox to podophyllin because podofilox results in less toxicity and can be self-administered by the
In a nonpregnant patient, podofilox gel or solution is the authors’ first choice. This antimitotic agent is either chemically synthesized or purified from naturally occurring podophyllin resin. Podofilox is used in the treatment of external genital warts or condyloma acuminatum. It is applied twice daily for 3 consecutive days and repeated for up to 4 weeks. Application stimulates visible necrosis of wart tissue. Side effects are minimal.
To ensure that the patient is fully aware of the correct method of therapy and to identify which specific warts should be treated, the prescriber should demonstrate the technique for initial application of the medication. No more than 0.5 g of gel per day should be used. Limit the total wart tissue …show more content…
It is a physician-applied medicine used in the treatment of external genital warts and condyloma acuminatum. It can be applied weekly for up to 6 weeks. Warts visible after 6 treatments usually do not respond to further therapy.
Podophyllin is applied directly to warts, but no more than 0.5 mL should be used with 1 treatment. Before application, thoroughly cleanse the affected area. Avoid contact with healthy tissue. Apply the medicine sparingly, and allow it to dry thoroughly. The initial application should be for 30-40 minutes; subsequent applications can be for 1-4 hours. Remove dried podophyllin with alcohol or with soap and water. Do not treat large areas or numerous warts at once.
Ulceration and pain are potential side effects of podophyllin therapy. In addition, special care must be taken in using this agent because it not only causes tissue injury but also can be absorbed systemically and cause neurologic toxicity. Deaths have occurred with the use of podophyllin on exuberant perianal warts; the surface area of the lesions increases the absorption of the drug. Podophyllin is contraindicated in pregnancy.
The authors prefer podofilox to podophyllin because podofilox results in less toxicity and can be self-administered by the