Product Doccription: Sermorelin: Product Description
Sermorelin : Product Description
Sermorelin is a synthetic hormone which was created to stimulate the production of Growth Hormone (GH) by the pituitary gland in the brain. It is a growth hormone-releasing hormone (GHRH) peptide analogue which contains a peptide sequence of 29 amino acids. It is the shortest synthetic peptide that has all the functional properties of GHRH since it is a copy of the active portion of the natural human GHRH. As such, it is a growth hormone secretagogue. GHRH is a hormone produced by the body naturally to stimulate the release of GH/hGH by the pituitary glands and it plays a major role in child growth. The production of HGH by the anterior pituitary gland is usually very high and growth rate is also usually at …show more content…
Since its discovery, the production of Sermorelin acetate has been carried out by Serono under the brand name GEREF. GEREF has been used in the diagnosis and treatment of growth hormone deficiency with additional uses in Anti-aging Therapy in combination with Testosterone in men. It has been widely used in adult hormone deficiency. In mid-2008, Serono terminated the production of GEREF after they obtained rights to a more expensive hormone, tesamorelin (another growth hormone releasing hormone). Tesamorelin is permitted in reducing abdominal fat in HIV patients who have lipodystrophy or visceral fat accumulation as a result of HIV and its medications. Due to its close links with increased growth of skeletal and muscular tissue, it is used in sports as a doping …show more content…
The researchers also observed that in children who had idiopathic GH deficiency, subcutaneous injections of sermorelin resulted in a statistically substantial increase in their height. This rise in growth rate could be sustained consistently over a period of 36 months. It was also observed that the two types of sermorelin administrations were very well tolerated as the only observable adverse effects were pain at the injection site and transient facial flushing. Based on this study, sermorelin initiates the secretion of GH by the adenohypophysis; intravenous administration of sermorelin may be applied in diagnosis of some cases of GH deficiency; and subcuteneous administration of sermorelin can effectively help manage GH
Sermorelin is a synthetic hormone which was created to stimulate the production of Growth Hormone (GH) by the pituitary gland in the brain. It is a growth hormone-releasing hormone (GHRH) peptide analogue which contains a peptide sequence of 29 amino acids. It is the shortest synthetic peptide that has all the functional properties of GHRH since it is a copy of the active portion of the natural human GHRH. As such, it is a growth hormone secretagogue. GHRH is a hormone produced by the body naturally to stimulate the release of GH/hGH by the pituitary glands and it plays a major role in child growth. The production of HGH by the anterior pituitary gland is usually very high and growth rate is also usually at …show more content…
Since its discovery, the production of Sermorelin acetate has been carried out by Serono under the brand name GEREF. GEREF has been used in the diagnosis and treatment of growth hormone deficiency with additional uses in Anti-aging Therapy in combination with Testosterone in men. It has been widely used in adult hormone deficiency. In mid-2008, Serono terminated the production of GEREF after they obtained rights to a more expensive hormone, tesamorelin (another growth hormone releasing hormone). Tesamorelin is permitted in reducing abdominal fat in HIV patients who have lipodystrophy or visceral fat accumulation as a result of HIV and its medications. Due to its close links with increased growth of skeletal and muscular tissue, it is used in sports as a doping …show more content…
The researchers also observed that in children who had idiopathic GH deficiency, subcutaneous injections of sermorelin resulted in a statistically substantial increase in their height. This rise in growth rate could be sustained consistently over a period of 36 months. It was also observed that the two types of sermorelin administrations were very well tolerated as the only observable adverse effects were pain at the injection site and transient facial flushing. Based on this study, sermorelin initiates the secretion of GH by the adenohypophysis; intravenous administration of sermorelin may be applied in diagnosis of some cases of GH deficiency; and subcuteneous administration of sermorelin can effectively help manage GH