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Psoriasis: A Disease Affecting the Integumentary System

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Psoriasis: A Disease Affecting the Integumentary System
Psoriasis | A disease affecting the integumentary system | Simaria HollandBio 201July 21,2011 | |

Psoriasis is a chronic auto-immune disease that appears on the skin. Psoriasis happens when the immune system sends out faulty signals that increase the production of skin growth resulting in the typical appearance of thickened, raised, and dry skin. It is estimated that 2% of the world 's population suffers from this disease. There is no "cure" for those living with this disease. Psoriasis is commonly seen in fair skinned individuals. But slowly the rate in dark skinned individuals is rising. People living with Psoriasis are also reportedly more depressed, and living with the disease myself, I can see why it would lead to depression in some individuals. I have chosen to cover this topic because I am one of the many of people who suffer from it. I understand first hand (literally) how this disease affects you not only physically but mentally. Though the name psoriasis was not introduced for many years the actual condition was talked about by Greek Physician, Hippocrates who lived between 460 and 377 BC. Psoriasis was then again mentioned by Cornelius Celsus, a Roman author. He described it as the fourth variant of impetigo caused by satphloccus pyogenes. This condition appeared as red patches with water blisters on the skin. English dermatologist Robert Willan recognized psoriasis as an independent disease with two categories: Leprosa Graecorum is the scaly condition of the disease and Psora Leprosa was when the condition became eruptive. In 1841 Ferdinand Hebra, a Viennese doctor gave psoriasis its name. By using Willians notes, Hebra helped bring insight to what is now known as Psoriasis. Prior to then, it was believed that people with Psoriasis were contagious and they were forced to live in leper colonies.
Psoriasis is a T-Cell mediated auto-immune disorder. Environmental factors, for example a virus, induces T-cells to form cytokines. The cytokines



Bibliography: Centric, S. (n.d.). http://www.sciencecentric.com/news/09012805-missing-genes-link-psoriasis.html. Retrieved from Science Centric. Health Spas.Co.ZA. (n.d.). Retrieved from http://www.healthspas.co.za/spa-articles-psoriasis.php. http://www.aaaomonline.info/ameracu/V46P20-Psoriasis.pdf. (n.d.). Retrieved from AAAM Online - TCM . MedicineNet. (n.d.). http://www.medicinenet.com/psoriasis/article.htm#look. Paoriasis.ORG. (n.d.). http://www.psoriasis.org. Retrieved from Paoriasis.ORG. Psoriasis. (n.d.). Retrieved from EveryDay Health: http://www.everydayhealth.com/psoriasis/inverse-psoriasis.aspx

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