pyridine
Reactions of pyridine Introduction:
1. Pyridine structure:
2. Iupac name: Pyridine, other name: Azine & Azabenzene.
*Important commercial alkyl pyridinium compound is α - methyl- pyridine (2), βpicoline (3), γ- picoline ( 4 ) , 2,6 - lutidine ( 5 ) , 3,5 - dimethyl- pyridine ( 6 ) ethyl-2 - methyl- pyridine ( 7 ) and 2,4,6 - collidine ( 8 ) . In general, the alkyl -substituted pyridine as many other precursors used in pyridine E-commerce. From these further alkyl substituted pyridine derivatives of pyridine compounds is often used in turn as an intermediate in the manufacture of Commercially useful end product.
1.Physical properties:
1.Pyridine physical properties are stable, cyclic, 6 results - π π- electron deficient , the aromatic ring structure containing a nitrogen atom.
2.Carbon Ring atom in the ring nitrogen stronger than the negative power , thus making the two , 4 - and 6 - ring carbon atom ratio , otherwise it will be more electropositive ,From the knowledge of the chemistry of the benzene ring can be expected . Aromatic π - electron system does not lone pair of electrons involved On the nitrogen atom , so that the term alkaline and π - pyridine compounds are described for defects . Pyridine ring through the nitrogen. The reaction is typically weak , organic tertiary amines such as protons , alkylation ( see ) , and acylation.
3.Pyridine and alkyl pyridines liquid are considered a dipolar aprotic solvent like dimethylformamide or dimethyl sulfoxide. Most Pyridine- water azeotrope formation with significant , separation of pyridine by steam distillation of the mixture can be separated by simple not Separate distillation. The same effect can also be water azeotropically dried quickly by a small forecut distilled water wet pyridine Azeotrop Pyridine. Many physical properties different from those of benzene, pyridine , with its counterpart elements . For example , the boiling point of
1. Pyridine structure:
2. Iupac name: Pyridine, other name: Azine & Azabenzene.
*Important commercial alkyl pyridinium compound is α - methyl- pyridine (2), βpicoline (3), γ- picoline ( 4 ) , 2,6 - lutidine ( 5 ) , 3,5 - dimethyl- pyridine ( 6 ) ethyl-2 - methyl- pyridine ( 7 ) and 2,4,6 - collidine ( 8 ) . In general, the alkyl -substituted pyridine as many other precursors used in pyridine E-commerce. From these further alkyl substituted pyridine derivatives of pyridine compounds is often used in turn as an intermediate in the manufacture of Commercially useful end product.
1.Physical properties:
1.Pyridine physical properties are stable, cyclic, 6 results - π π- electron deficient , the aromatic ring structure containing a nitrogen atom.
2.Carbon Ring atom in the ring nitrogen stronger than the negative power , thus making the two , 4 - and 6 - ring carbon atom ratio , otherwise it will be more electropositive ,From the knowledge of the chemistry of the benzene ring can be expected . Aromatic π - electron system does not lone pair of electrons involved On the nitrogen atom , so that the term alkaline and π - pyridine compounds are described for defects . Pyridine ring through the nitrogen. The reaction is typically weak , organic tertiary amines such as protons , alkylation ( see ) , and acylation.
3.Pyridine and alkyl pyridines liquid are considered a dipolar aprotic solvent like dimethylformamide or dimethyl sulfoxide. Most Pyridine- water azeotrope formation with significant , separation of pyridine by steam distillation of the mixture can be separated by simple not Separate distillation. The same effect can also be water azeotropically dried quickly by a small forecut distilled water wet pyridine Azeotrop Pyridine. Many physical properties different from those of benzene, pyridine , with its counterpart elements . For example , the boiling point of
References: 1. W. Ramsay, Ber. Dtsch. Chem. Ges. 10, 736 (1877). 2. T. Anderson, J. Liebigs Ann. Chem. 60, 86 (1846). 3. A. E. Chichibabin, Zh. Russ. Fiz. Khim. O-va. 37, 1229 (1905). 4. A. P. Kudchadker and S. A. Kudchadker, Pyridine and Phenylpyridines, API Publication 710, American Petroleum Institute, Washington, D.C., 1979. 5. Technical data, Reilly Industries, Indianapolis, Ind. 6.Eric F. V. Scriven. "Pyridine and Pyridine Derivatives", Kirk-Othmer Encyclopedia of Chemical Technology, 12/02/2005.