Anthony Lulgjuraj
Fly Lab Report
Friday 9:30am
Mutation #620 X Mutation #644
1) The vial labeled Mutation #620 contained female flies that displayed a mutation in eye color. This mutation causes a change in eye pigment from wild type (bright red) to a dark, reddish brown. The males possessed mutation #644. It is a mutation in wing morphology that reduces wing size. A controlled cross was conducted between these two true-breeding mutant flies. Their progeny (F1) being heterozygous for both mutations displayed only wild type phenotypes. These two mutations in Drosophila are both believed to follow an autosomal recessive pattern of inheritance.
Figure 1. Images Drosophila melanogaster with mutations. From left to right, mutation in eye color (e), mutation in wing morphology (w). A controlled cross was performed between a true-breeding fly with the eye color mutation and a true-breeding fly with the wing mutation.
P1
F1
Figure 2. A pedigree showing the pattern of inheritance for a mutation in eye color and a mutation in wing morphology. Both mutations are recessive and their alleles are represented as e/e; w/w.
Symbols with the left half shaded have a mutation in eye color and normal wings. Making the parental female’s genotype e/e; w+/w+. Symbols with the right half shaded have wild type eyes and a mutation with wing morphology. This gives rise to the parental male’s genotype, e+/e+; w/w.
All of the F1’s are heterozygous for there genotype, e/e+; w/w+, and display wild type phenotypes.
Table 1. Data collected from observing the phenotypes of the F1 offspring from the controlled cross.
All progeny were phenotypically wild type.
F1
Males
Females
Wild Type
15
17
Mutation #620
0
0
Mutation #644
0
0
Other Phenotype
0
0
P1
F1
F1
F2
Figure 3. This pedigree represents the pattern of inheritance in all three generations. Symbols with the left half shaded just have an eye color mutation. Symbols with the right half shaded just have
wing