A Case Presentation on Rheumatic Heart Disease
General Data: V.V., 25 years old, female, married, housewife, residing at Balibago, Angeles City was admitted for the first time at AUFMC on February 6, 2014
Chief Complaint: Chest pain
History of Present Illness: The illness started 2-1/2 years ago, when she started to experience occasional chest pain, lasting only for a few seconds especially during her aerobic exercise but does not incapacitate her. It did relieved by just resting. She did not bother to consult, thinking it was only the result of over-exercise. It did not affect her daily routine works.
A year prior to consult, she noticed that her precordial had increased in intensity and last longer compared to those the previous ones. This manifestation of symptoms was experienced more after having an abortion but …show more content…
She was rushed to AUF emergency room and subsequently …show more content…
Cross-reactive epitopes are present in the streptococcal M protein and the N-acetylglucosamine of group A streptococcal carbohydrate and are immunologically similar to molecules in human myosin, tropomyosin, keratin, actin, laminin, vimentin, and N acetylglucosamine. It is currently thought that the initial damage is due to cross-reactive antibodies attaching at the cardiac valve endothelium, allowing the entry of primed CD4+ T cells, leading to subsequent T cellmediated inflammation. Episodes of recurrent ARF will result to repeated or ongoing infections possibly driving the valvular inflammatory response ultimately resulting to rheumatic heart