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Rimantadine Research Paper

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Rimantadine Research Paper
Rimantadine hydrochloride is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
In a variety of tissue culture systems, rimantadine (25 µg/ml) completely suppressed the growth of dengue virus type 2 in human peripheral blood leukocytes (PBL). Rimantadine significantly inhibited dengue virus replication in cultures of rhesus monkey PBL. In virus-infected LLC-MK2 cell cultures, rimantadine decreased the production of all four types of dengue virus [1]. Rimantadine interfered with the generation of cellular immune responses. Rimantadine hydrochloride inhibited the proliferative response of human peripheral blood lymphocytes to mitogenic and antigenic stimulation. Rimantadine hydrochloride
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