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Introduction Relevant nursing issue Some of the questions that arise from women living with HIV are barrier to social services. It affects the livelihood of women; thus, they are unable to acquire some essential services. Another issue is that they have mental health problem; thus, they are placed at a higher risk for HIV infection. They also face stigmatization that is rooted in discrimination (Peninnah, 2013). Other issues that arise are limitation to children health care, misinformation regarding treatment options, lack of access to transportation, substance abuse in regard to treatment, and unstable housing. There are attempts that have been put to measure and understand one’s health status. The rules also incorporate the physical wellbeing, psychological status, and cognitive functioning (Deanna, 2013). The tests are referred to as Health-related quality of life (HRQoL). It is a way of knowing how individuals feel about their health. It is done from an interactive and interpretive point of view. It enables an empathetic understanding of daily life experience is different life settings. HRQoL also enhances the identification of the different race, gender, class and social positioning. It also considers social cultural and political forces. It has been knotted that, PLHIV have a lower physical and mental HRQoL score. It has also been knotted that women are mostly affected when compared to the male counterparts (Peninnah, 2013). Literature review From the research that done previously, it has indicated that, HIV-related stigmatization may be connected with mental, psychological and emotional health. The stigma has been associated with despair, stress, loneliness, depression, anxiety,