School
Final Exam Genetics Spring 2011
Student Name: ___________________________________________________________________________
Please see me if you have any questions
1. Which of the following is NOT a common consequence of mutations that eliminate cell-cycle checkpoints?
A. polyploidy
B. increased chromosomal translocations
C. increased DNA damage
D. aneuploidy
E. Increased apoptosis
2. Attenuation is fine tuning of gene regulation of operons for enzymes associated with anabolic (chemical building) pathways, such as the Trp operon for tryptophan synthesis. Which of the following is NOT true about this system:
A. Tryptophan is an amino acid
B. Attenuation does not occur in eukaryotes
C. During attenuation tryptophan molecules directly inhibit transcription of the Trp operon
D. Tryptophan in the cell affects the rate of translation of tryptophan codons near the start of the Trp protein
E. Presence of excess tryptophan results in premature termination of transcription.
3. The cell-cycle checkpoint that occurs during mitosis causes nuclear division to pause until
A. DNA replication is complete.
B. all chromosomes have attached to the mitotic spindle.
C. cytokinesis occurs.
D. telophase begins.
E. chromosomes have fully condensed (shortened).
4. DNA replication occurs during ______ of the cell cycle.
A. prophase
B. G1 phase
C. mitosis
D. G2 phase
E. S phase
5. Three point crosses are used to determine:
A. The exact location of the chiasmata
B. The order of genes based on parentals and recombinants
C. The probability of independent assortment
D. The location of a single nucleotide polymorphism
E. Segregation patterns of ascospores
6. A _____________________ is a cis-acting DNA sequence that functions to regulate a cluster of two or more related genes.
A. basal protein
B. promoter
C. locus control region
D. derepressor
E. transcriptional activator
7.
Student Name: ___________________________________________________________________________
Please see me if you have any questions
1. Which of the following is NOT a common consequence of mutations that eliminate cell-cycle checkpoints?
A. polyploidy
B. increased chromosomal translocations
C. increased DNA damage
D. aneuploidy
E. Increased apoptosis
2. Attenuation is fine tuning of gene regulation of operons for enzymes associated with anabolic (chemical building) pathways, such as the Trp operon for tryptophan synthesis. Which of the following is NOT true about this system:
A. Tryptophan is an amino acid
B. Attenuation does not occur in eukaryotes
C. During attenuation tryptophan molecules directly inhibit transcription of the Trp operon
D. Tryptophan in the cell affects the rate of translation of tryptophan codons near the start of the Trp protein
E. Presence of excess tryptophan results in premature termination of transcription.
3. The cell-cycle checkpoint that occurs during mitosis causes nuclear division to pause until
A. DNA replication is complete.
B. all chromosomes have attached to the mitotic spindle.
C. cytokinesis occurs.
D. telophase begins.
E. chromosomes have fully condensed (shortened).
4. DNA replication occurs during ______ of the cell cycle.
A. prophase
B. G1 phase
C. mitosis
D. G2 phase
E. S phase
5. Three point crosses are used to determine:
A. The exact location of the chiasmata
B. The order of genes based on parentals and recombinants
C. The probability of independent assortment
D. The location of a single nucleotide polymorphism
E. Segregation patterns of ascospores
6. A _____________________ is a cis-acting DNA sequence that functions to regulate a cluster of two or more related genes.
A. basal protein
B. promoter
C. locus control region
D. derepressor
E. transcriptional activator
7.