Scientific Researches Proving Weight Loss from Atkins Diet

PUBLISHED STUDIES SUPPORTING ATKINS
Author Accurso Year Title 2008 Dietary Carbohydrate Restriction in Type 2 Diabetes Mellitus and Metabolic Syndrome: Time For a Critical Appraisal Journal Nutrition & Metabolism University/Funding n/a This is a review article. Summary Experiments are summarized showing that carbohydraterestricted diets are at least as effective for weight loss as low-fat diets and that substitution of fat for carbohydrate is generally beneficial for risk of cardiovascular disease. These beneficial effects of carbohydrate restriction do not require weight loss. Finally, the point is reiterated that carbohydrate restriction improves all of the features of metabolic syndrome.

Arvio

2010 Modified Atkins Diet Brought Back The Duodecim Joy of Life to a Developmentally Severely Disabled Youth

Paijat-Hame Central Hospital, Authors describe a developmentally severely disabled man, Neurology and Internal Medicine whose epilepsy settled, autistic features were alleviated, Clinics/Funding not listed. behavioral problems disappeared and whose weight and blood lipid and glucose values have remained normal for one year during a modified Atkins diet. Agatston Research Institute/Agaston Research Institute Compared with the NCEP diet, the MLC diet, which is lower in total carbohydrates but higher in complex carbohydrates, protein, and monounsaturated fat, caused significantly greater weight loss over 12 weeks. Weight loss was significantly greater in the Modified Low Carbohydrate (13.6 lb) than in the National Cholesterol Education Program group (7.5 lb), a difference of 6.1 lb. There were significantly favorable changes in all lipid levels within the MLC but not within the NCEP group. Waist-to-hip ratio was significantly decreased within the MLC group.

Aude

2004 The National Cholesterol Education Program Diet vs a Diet Lower in Carbohydrates and Higher in Protein and Monounsaturated Fat

Arch Intern Med

Austin

2009 A Very Low-carbohydrate Diet Clin Gastroenterol UNC General Clinical Research Improves Symptoms and Quality of Hepatol Center/Atkins Foundation Life in Diarrhea-Predominant Irritable Bowel Syndrome

Participants with moderate to severe IBS-D were provided a 2week standard diet, then 4 weeks of a VLCD (20 g carb/day). 77% of participants experienced adequate relief , improved abdominal pain, stool habits and quality of life regarding IBS-D as a result of VLCD.

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PUBLISHED STUDIES SUPPORTING ATKINS
Author Bailes Year Title Journal University/Funding 2003 Effect of Low-Carbohydrate, Unlimited Metabolic Marshall University/Funding not Calorie Diet on the Treatment of Syndrome and listed Childhood Obesity: A Prospective Related Disorders Controlled Study Summary Obese children following a high protein, low CHO diet (50% improvement; 19 (35%) were seizure-free.

Chen

Coleman

2005 Urinary Ketones Reflect Serum Ketone J Am Diet Assoc Concentration But Do Not Relate to Weight Loss in Overweight Premenopausal Women Following a Low-carbohydrate/High-protein Diet

Virginia Polytechnic Institute, Thirteen overweight premenopausal women aged 32 to 45 years Virginia State University/Funding consumed 50% decrease in seizure frequency, and 6 (25%) had >90% improvement, of whom 5 were seizure-free. Mean seizure frequency after the first, second and third months of treatment were significantly lower than at baseline. The Atkins diet can be considered as a safe and effective alternative therapy for intractable childhood epilepsy. Atkins diet was well tolerated in our patients with rare complications and it appears to demonstrate preliminary efficacy in childhood refractory epilepsy.

Tonekaboni

2010 Efficacy of the Atkins Diet as Therapy for Intractable Epilepsy in Children

Archives of Iranian Research Institute of Endocrine Medicine Sciences, Shahid Beheshti Medical University/Funding not listed.

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PUBLISHED STUDIES SUPPORTING ATKINS
Author Veldhorst Year Title Journal 2010 Presence or absence of carbohydrates British Journal of and the proportion of fat in a Nutrition highprotein diet affect appetite suppression but not energy expenditure in normal weight human subjects fed in energy balance University/Funding Maastricht University / Top Institute Food and Nutrition (Netherlands) Summary Appetite suppression and fat oxidation were higher on a highprotein diet without than with carbohydrates exchanged for fat. Energy expenditure was not affected by the carbohydrate content of a high-protein diet.

Vernon

2004 Clinical Experience of a Carbohydrate- Metabolic Duke University Medical Restricted Diet for the Metabolic Syndrome and Center/Atkins Foundation Syndrome Related Disorders

In this outpatient program, a carbohydrate-restricted diet and a low-fat/low-calorie plus medication led to weigh loss, but the carbohydrate-restricted diet had a more favorable effect on triglycerides and HDL. Because of the side effects on weight, triglycerides, and HDL, a carbohydrate-restricted diet may be useful for the treatment of metabolic syndrome. Low carbohydrate diets lead to a marked improvement in glucose homeostasis in association with a reduction in antidiabetic therapy and weight loss. These findings show that a 12-week low-carbohydrate diet improves postprandial vascular function more than a LFD in individuals with atherogenic dyslipidemia.

Vernon

Volek

2003 Clinical Experience of a Carbohydrate- Metabolic University of Kansas School of Restricted Diet: Effect on Diabetes Syndrome and Medicine and Duke University Mellitus Related Disorders Medical Center/Funding not listed. 2009 Effects of Dietary Carbohydrate Metabolism University of Restriction Versus Low-fat Diet on Connecticut/University of Flow-mediated Dilation. Connecticut, US; Department of Agriculture Hatch, Atkins Foundation, Egg Nutrition Center, and the Research Foundation of the State University of New York.

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PUBLISHED STUDIES SUPPORTING ATKINS
Author Volek Year Title 2009 Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet Journal Lipids University/Funding University of Connecticut/University of Connecticut, US; Department of Agriculture Hatch, Atkins Foundation, Egg Nutrition Center, and the Research Foundation of the State University of New York Summary Both interventions led to improvements in several metabolic markers, but subjects following the CRD had consistently reduced glucose (-12%) and insulin (-50%) concentrations, insulin sensitivity (-55%), weight loss (-10%), decreased adiposity (-14%), and more favorable triacylglycerol (TAG) (-51%), HDL-C (13%) and total cholesterol/HDL-C ratio (-14%) responses. In addition to these markers for MetS, the CRD subjects showed more favorable responses to alternative indicators of cardiovascular risk: postprandial lipemia (-47%), the Apo B/Apo A-1 ratio (-16%), and LDL particle distribution. The results support the use of dietary carbohydrate restriction as an effective approach to improve features of MetS and cardiovascular risk.

Volek

2004 Comparison of a Very LowCarbohydrate and Low-Fat Diet on Fasting Lipids, LDL Subclasses, Insulin Resistance, and Postprandial Lipemic Responses in Overweight Women

J Am Coll Nutr

University of Connecticut/Atkins Compared to a low-fat weight loss diet, a short-term very lowFoundation carbohydrate diet did not lower LDL-C but did prevent the decline in HDL-C and resulted in improved insulin sensitivity in overweight and obese, but otherwise healthy women. Small decreases in body mass improved postprandial lipemia, and therefore cardiovascular risk, independent of diet composition. This study shows a clear benefit of a VLCK over LF diet for shortterm body weight and fat loss, especially in men. A preferential loss of fat in the trunk region with a VLCK diet is novel and potentially clinically significant but requires further validation.

Volek

2004 Comparison of Energy-restricted Very Nutr Metab (Lond) University of Connecticut/Atkins Low-carbohydrate and Low-fat Diets Foundation on Weight Loss and Body Composition in Overweight Men and Women

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