Sickle Cell
Evolution of Sickle Cell
Sickle Cell was discovered in the United states although it originated in Africa . The sickle cell disease (SCD) describes traits of an inherited red blood cell disorder, having SCD means you have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in your red blood cells.
What is hemoglobin u might ask?! Well
Hemoglobin is a protein in red blood cells that is suppose to carry oxygen throughout the body. But when a sickle cell trait is “Inherited” it could only mean that the disease was passed on by genes from parents to their children. SCD is not contagious and cannot be sexual transmitted. In order for a person to contract hemoglobin S they would have to receive one normal and one abnormal from one infected parent, at least one of the two abnormal genes causes a person’s body to make hemoglobin S. People who become infected with SCD inherit two abnormal hemoglobin genes, one from each parent.When a person has two hemoglobin S genes, Hemoglobin SS, the disease is known as sickle cell anemia. This seems to be the most common and often the most extreme kind of SCD.
Hemoglobin SS starts from lack of oxygen …show more content…
The malaria parasite metabolizes food and produces carbon dioxide as a waste product. This carbon dioxide, when in an an environment like that inside a red blood cell, forms carbonic acid. Because of these high levels of C02 and acid, the hemoglobin in a parasitized red blood cell tends to be in the deoxygenated form. If a red blood cell contains S hemoglobin and a malarial parasite, the S hemoglobin will be deoxygenated, aggregate, and sickle the red blood
Sickle Cell was discovered in the United states although it originated in Africa . The sickle cell disease (SCD) describes traits of an inherited red blood cell disorder, having SCD means you have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in your red blood cells.
What is hemoglobin u might ask?! Well
Hemoglobin is a protein in red blood cells that is suppose to carry oxygen throughout the body. But when a sickle cell trait is “Inherited” it could only mean that the disease was passed on by genes from parents to their children. SCD is not contagious and cannot be sexual transmitted. In order for a person to contract hemoglobin S they would have to receive one normal and one abnormal from one infected parent, at least one of the two abnormal genes causes a person’s body to make hemoglobin S. People who become infected with SCD inherit two abnormal hemoglobin genes, one from each parent.When a person has two hemoglobin S genes, Hemoglobin SS, the disease is known as sickle cell anemia. This seems to be the most common and often the most extreme kind of SCD.
Hemoglobin SS starts from lack of oxygen …show more content…
The malaria parasite metabolizes food and produces carbon dioxide as a waste product. This carbon dioxide, when in an an environment like that inside a red blood cell, forms carbonic acid. Because of these high levels of C02 and acid, the hemoglobin in a parasitized red blood cell tends to be in the deoxygenated form. If a red blood cell contains S hemoglobin and a malarial parasite, the S hemoglobin will be deoxygenated, aggregate, and sickle the red blood