Sleep Homeostasis

Homeostasis, in general, the sleep-wake cycle is regulated by two separate biological mechanisms in the body which interact together and balance each other. Studies say that high levels of adenosine leads to sleepiness. According to the two process model of sleep regulation the timing and structure of sleep are determined by the interaction of a homeostatic and a circadian process. The original qualitative model was elaborated to quantitative versions that included the ultradian dynamics of sleep in relation to the non rem-rem sleep cycle. The time course of eeg slow wave activity is the major marker of non rem sleep homeostasis as well as daytime alertness were simulated successfully for a considerable number of experimental protocols. They