Solanum nigrum Linn. commonly known as Black Nightshade is a dicot weed in the Solanaceae family. Other names of S. nigrum are European Black Nightshade or just black nightshade, Duscle, Garden Nightshade, Hound’s Berry, Petty Morel, Wonder Berry, Small-fruited black nightshade. It is a species of the Solanum genus, native to Eurasia and introduced in the Americas, Australia, Asia and South Africa. The plant is cultivated as a food crop, both for its fruit and its leaves in some parts of the world. Ripe berries and cooked leaves are used as food in some locales; Parts of this plant can be highly toxic to livestock and humans, and it is considered a weed. The toxicity can vary considerably according to where the plant is grown …show more content…
Several studies indicated that S. nigrum exhibited anti-ulcer, anti-tumor, antioxidant, anti-inflammatory, hepato-protective, diuretic and antipyretic, anti-microbial, anti-cancer, anti ulcerogenic, cytotoxic properties and …show more content…
nigrum possesses various compounds that are responsible for diverse activities. The major active components are glycoalkaloids, glycoproteins, and polysaccharides. It also contains polyphenolic compounds such as gallic acid, catechin, protocatechuic acid (PCA), caffeic acid, epicatechin, rutin, and naringenin. The glycoalkaloids include solamargine, solasonine, and solanine that belong to the tropane group of compounds. Jain R, Khattak JZ 2012
Solanine’s function and activity has been extensively studied. It comprises 95 percent of the total alkaloid concentration present in the plant and is found naturally in any part. It is one of the plant’s major natural defenses as it is toxic even in small quantities with a molecular weight of 868.04 and formula C45H73NO15. It consists of an aglycone, solanidine (alkaloidal portion), and three sugar moieties (glucose, galactose, and rhamnose, collectively known as solatriose), which are attached to the third position of the aglycone. It is generally present in the form of α-solanine, but can be hydrolyzed to β- and γ-solanine with one or two carbohydrate molecules each. Yen GC