Spontaneous Bacterial Peritonitis

Features and outcomes of spontaneous bacterial peritonitis in Egypt, single center experience prospective study

Spontaneous bacterial peritonitis (SBP) is the infection of the ascetic fluid that occur in the absence of a visceral perforation and in the absence of an intraabdominal inflammatory focus such as abscess, acute pancreatitis or cholecystitis (Guarner C and Soriano G, 2007). Since its initial description in 1964, research has transformed spontaneous bacterial peritonitis (SBP) from a feared disease (with reported mortality of 90%) to a treatable complication of decompensated cirrhosis, with steady prevalence and a high recurrence rate (Anastasios Koulaouzidis et al., 2009).
Of patients with cirrhosis who have spontaneous bacterial peritonitis, 70% are Child-Pugh class C. In these patients, the development of spontaneous bacterial peritonitis is associated with a poor long-term prognosis. (Steven M Bandy, 2009). According to some recent statistic data, hepatic cirrhosis represents the tenth major cause of death in USA (Amadon MA, Arroyo V, 2003). recurrence rate of up to 70% at 1 yr (Guarner C, Soriano G, 2007).Mortality rate ranges from 40-70% in adult patients with cirrhosis. Mortality may be decreasing because of advances in its diagnosis and treatment ( Steven M Bandy, 2009).
SBP pathogenesis was
We excluded from this study, Patients with secondary bacterial peritonitis and non-cirrhotic causes of ascites such as tuberculosis or malignancy, patients received systemic antibiotics for any other infection (s) or exposed to paracentesis or endoscopy within 7