Summary table of the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 used for Assessing Oral Mucositis:
Grade Symptoms (Clinical Scale)
Comments (Functional Scale)
Grade 1
Painless Ulcers and mild oral soreness with Erythema
Minimal Symptoms
1. Normal diet tolerable
2. Minimum respiratory symptoms
Grade 2
Painful Erythema, Ulcers present but can eat and swallow
1. Symptomatic but can eat and swallow modified diet.
2. Symptoms not badly interfering with activity of daily living
Grade 3
Painful Erythema, Oedema, Oral Ulcers are present. Patient only able to ingest liquids or may require IV hydration
1. Symptomatic and Unable to adequately
aliment or hydrate orally.
2. Symptoms which interferes with activity of daily living
Grade 4
Oral Mucositis to the extent that Oral alimentation is not possible. Severe ulceration
Symptoms associated with life threatening consequences
Grade 5 Death
Death
Measurement of Oral Mucositis. National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 3.0. Retrieved from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266835/table/T2/