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Synthesis Of 1-4 Dioxane Lab Report

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Synthesis Of 1-4 Dioxane Lab Report
ESTIMATION OF 1-4, DIOXANE IN SHAMPOOS/ CONDITIONERS/HAIR CREAMS/ SODIUM LAURETH SULFATE BY HEAD SPACE GAS CHROMATOGRAPHIC TECHNIQUE
INTRODUCTION
1-4, DIOXANE
1,4-Dioxane is a heterocyclic organic compound, classified as an ether. It is a colorless liquid with a faint sweet odor similar to that of diethyl ether. The compound is often called simply Dioxane because the other Dioxane isomers (1,2- and 1,3-) are rarely encountered.
CHEMISTRY OF 1-4, DIOXANE TOXICOLOGY
Dioxane has an LD50 of 5170 mg/kg, making it less acutely toxic than table salt (3000 mg/kg).This compound is irritating
…show more content…
WHAT IS 1, 4 DIOXANE?

1, 4-dioxane is generated through a process called ethoxylation, in which ethylene oxide, a known breast carcinogen, is added to other chemicals to make them less harsh
This process creates 1, 4-dioxane. For example, sodium laurel sulfate, a chemical that is harsh on the skin, is often converted to the less-harsh chemical sodium laureth sulfate (the “eth” denotes ethoxylation). The conversion process can lead to contamination of this ingredient with 1,4-dioxane. Other common ingredients that may be contaminated by 1,4-dioxane include PEG compounds and chemicals that include the clauses “xynol,” “ceteareth” and “oleth”. Most commonly, 1,4-dioxane is found in products that create suds, like shampoo, liquid soap and bubble bath. Environmental Working Group’s analysis suggests that 97 percent of hair relaxers, 57 percent of baby soaps and 22 percent of all products in Skin Deep may be contaminated with 1,4-dioxane [1]. Independent lab tests co-released by the Campaign for Safe Cosmetics in 2007 showed that popular brands of children’s bubble bath and body wash contained 1, 4-dioxane

HEALTH CONCERNS:

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