life-threatening.
life-threatening.
A 45-year-old female has elevated thyroxine production. Which of the following would accompany this condition?…
it may also involve the blood vessels, skin, eye, nerves, heart, and lungs. It is seen in women…
Right lymphatic duct—collects from right upper arm, right side of head and thorax. Empties into R Subclavian vein…
7) In the inflammatory response, the absence of which of the following would prevent all the others from happening?…
Tay-Sachs disease is a rare inherited autosomal recessive disorder first discovered in 1881. It is a disease that is found in many populations, but commonly affects the populations of the Ashkenazi Jews. The disorder is caused when there is an absence of enzyme called beta hexosaminase A that is found on chromosome 15. The most common mutation occurs in mostly 80 percent of Tay-Sachs patients is the four base pair addition (TATC) on exon 11 and a G to C inversion at the splice junction of intron 12 which leads to a miss spliced and causes the messenger RNA to be unstable; and a G to A inversion on exon 7 of the hexosaminase A gene. The insertion of this base pair causes the codon to stop early which then causes a hexosaminase A deficiency (Amos Frisch). Tay-Sachs is a lethal disease.…
Most episodes of SVT are caused by faulty electrical connections in the heart. What causes the electrical problem is not clear. SVT also can be caused by certain medicines. Examples include very high levels of the heart medicine digoxin or the lung medicine theophylline. Some types of SVT may run in families. Or they may be caused by a lung problem such as COPD or pneumonia. The condition most occurs in young people or infants…
In children with Tay-Sachs disease, a faulty gene on chromosome 15 (HexA) causes the body to not produce the enzyme B-Hexosaminidase A. This means that the fatty substance (ganglioside) builds up in the brain and spinal cord, significantly damaging brain cells and therefore resulting in death.…
Tay-Sachs disease is a fatal genetic disorder that results in progressive destruction of the nervous system. Tay-Sachs is caused by the absence of the enzyme hexosaminidase A (Hex-A). Without Hex-A fatty proteins build up in the brain which cause damage to the brain cells. This damage causes children to loss motor skills and mental functions which overtime can cause the children to become blind, deaf, mentally retarded and nonresponsive to the environment.…
A rare and fatal disease, Tay-Sachs is characterized as one of the devastating neurodegenerative disease. Children afflicted with Tay-Sachs “lose motor skills and mental functions” eventually becoming “blind, deaf, mentally retarded, paralyzed...Tay-Sachs children usually die by age five” (“Tay-Sachs Disease”). A diagnosis of infantile Tay-Sachs is akin to a death sentence; the only form of care would be comfort for death. Tay-Sachs is passed on genetically from parent to child and, as it is an autosomal recessive disorder, “When both parents are carriers, there is a 1 in 4 (25%) chance, with every pregnancy, of having a child with Tay-Sachs disease...a 2 in 4 (50%) chance...of having a child who is a Tay-Sachs carrier” (Tay-Sachs Disease).…
If your chest muscles are affected by the disease, you may experience breathing problems, such as shortness of breath, or in severe cases, respiratory failure. Late in the disease, particularly if you’ve had the disease for a long…
Sickle-cell disease is a genetic disorder that results from the abnormal structure of red blood cells. The peculiar shape of the red blood cell prevents the normal absorption of oxygen. This disease results from the abnormal production of hemoglobin S (HbS). Therefore, a mutation in this gene causes a lower supply of oxygen to the cells, which results in occlusion of the blood vessels. Individuals diagnosed with sickle-cell anemia have abnormal function of the gene that encodes for subunit B, which is a protein that serves as part of the hemoglobin A (HbA). The HbA is responsible for oxygen binding through the blood stream. Indeed, the abnormal polymerization of hemoglobin occurs in homozygous individuals with sickle-cell anemia, which lowers the oxygen supply of red blood cells. To lower the negative consequences of sickle-cell anemia, it is necessary to provide a better understanding of the genetic material that underlies the sub-phenotype of sickle-cell anemia. Therefore, this could help in the discovery of drugs that could target the genes responsible for sickle-cell anemia.…
Multiple sclerosis [MS] is a chronic, autoimmune, inflammatory, neurodegenerative condition of the central nervous system [CNS] (Boppanna, Huang, Ito & Dhib-Jalbut, 2011) characterized by demyelination and axonal loss (Chastain, Duncan, Rodgers & Miller, 2011). MS expresses itself in 4 forms: relapsing remitting MS [RRMS], secondary progressive MS [SPMS], primary progressive MS [PPMS], and progressive relapsing MS [PRMS] (Boppanna, Huang, Ito & Dhib-Jalbut, 2011). MS affects 0.1 per cent of the world’s population (Chastain, Duncan, Rodgers & Miller, 2011), occurring 2- and 2.5-fold more frequently in women than in men, having an incidence range of post-pubertal teenagers to adults in their 50’s (Calabresi, 2011).…
Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)…
More than 300,000 people in the United States and over 1 million people worldwide are diagnosed with MS. The disease generally strikes women twice as often as men, between the ages of 20 to 40. The signs and symptoms of MS can vary widely depending on the individual and the specific nerves that may be affected. Some symptoms include abnormal sensations such as tingling, weakness or numbness in the arms or legs and possibly…
Sickle cell disease is present usually in those of African or Mediterranean descent (Saladin 2007). About 1.3% of African Americans have sickle cell (Saladin, 2007). Sickle cell was originated in Africa where malaria was killing a vast number of people (Saladin, 2007). The sickle cell hemoglobin is not able to be digested by the parasites that cause malaria, making those with sickle cell resistant to malaria (Saladin, 2007). This paper will discuss a normal erythrocyte compared to an erythrocyte affected with sickle cell. It will also talk about how to diagnose sickle cell disease.…