Tablet Manufacturing Area
TABLET MANUFACTURING AREA:
TABLET: A tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.
TABLET MANUFACTURING PROCESS:
1. Batch Manufacturing Record
Any production in the pharmaceutical industry is followed strictly and blindly according to previously developed protocols. So for production, the entire process, precautions, equipment, conditions to be maintained are mentioned in the Batch Manufacturing Record (BMR). This BMR is documented by the R&D unit and checked for improvements by the Analytical Development unit. 2. Dispensing Of Raw Material
Dispensing is the first step in any pharmaceutical manufacturing process. Dispensing is one of the most critical step in pharmaceutical manufacturing; as during this step, the weight of each ingredient in the mixture is determined according to dose. Dispensing may be done by purely manual by hand scooping from primary containers and weighing each ingredient by hand on a weigh scale, manual weighing with material lifting assistance like Vacuum transfer and Bag lifters, manual or assisted transfer with automated weighing on weigh table, manual or assisted filling of loss-in weight dispensing system, automated dispensaries with mechanical devices such as vacuum loading system and screw feed system. Issues
TABLET: A tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.
TABLET MANUFACTURING PROCESS:
1. Batch Manufacturing Record
Any production in the pharmaceutical industry is followed strictly and blindly according to previously developed protocols. So for production, the entire process, precautions, equipment, conditions to be maintained are mentioned in the Batch Manufacturing Record (BMR). This BMR is documented by the R&D unit and checked for improvements by the Analytical Development unit. 2. Dispensing Of Raw Material
Dispensing is the first step in any pharmaceutical manufacturing process. Dispensing is one of the most critical step in pharmaceutical manufacturing; as during this step, the weight of each ingredient in the mixture is determined according to dose. Dispensing may be done by purely manual by hand scooping from primary containers and weighing each ingredient by hand on a weigh scale, manual weighing with material lifting assistance like Vacuum transfer and Bag lifters, manual or assisted transfer with automated weighing on weigh table, manual or assisted filling of loss-in weight dispensing system, automated dispensaries with mechanical devices such as vacuum loading system and screw feed system. Issues