Human growth hormone (HGH) is produced by the pituitary gland within the body. One of its main functions is to increase growth in children and adolescents as they get older. HGH also helps regulate body composition, body fluids, muscle and bone growth, sugar and fat metabolism, and in some aspects, heart function. Human growth hormone can also be produced synthetically. The synthetic form of HGH is an active ingredient in a number of prescription drugs and in other products that are widely available in today’s society over the Internet and through various illegal drug dealers among communities.
Synthetic human growth hormone was originally created by a pharmaceutical manufacturer in 1985. Prior to the development of synthetic HGH, scientists and doctors extracted it from corpses to treat patients that suffered from growth deficiency. Many of them later died from Creutzfeldt-Jakob disease, a disease in which the brain would become spongy and eventually deteriorate. As a result scientists believed the disease was related to a virus found in the extracted hormone. Approximately six months after the Food and Drug Administration banned the cadaver-extracted hormone, a biotechnology company had successfully developed synthetic human growth hormone. The Food and Drug Administration (FDA) would only allow the use of synthetic HGH under specific conditions. Injections of HGH were only approved for patients that needed to be treated for growth deficiency due to unknown or medical causes. Some of these conditions that authorized the use of man-made HGH were Turner’s syndrome, Prader-Willi syndrome, kidney insufficiency, HGH deficiency and muscle-wasting diseases such as those linked to HIV and AIDS. As the use of synthetic human growth hormone increased globally, scientists began to explore the effects of HGH not only on growth deficient patients, but also on healthy
References: Bidlingmaier, Martin & Strasburger, Christian. (2007) Technology Insights: Detecting Growth Hormone Abuse in Athletes. nature clinical practice ENDOCRINOLOGY & METABOLISM: vol 3 no 11 Conrad, Peter & Potter, Deborah Davy, Emma. (2011) The Real Dopes. , Current Science, 00113905,Vol. 86, Issue 2. EBSCO. Retrieved from http://search.ebscohost.com DiConsiglio, John FTC Consumer Alert. (2005) “HGH” Pills and Sprays: Human Growth Hype? Healy, Marie-Louise Healy, Marie-Louise. (2008) The Journal of Clinical Endocrinology & Metabolism 88(11):5221–5226 High Dose Growth Hormone Exerts on Anabolic Effect at Rest and During Exercise in Endurance-trained Athletes. The Endocrine Society Linnaeus, Tomas Mchugh, Cathy. (2005) Clinical Chemistry 51, No. 9. Abuse of Growth Hormone in Sport Sonksen, P.H. Thieme, Detlef & Hemmersbach, Peter. (2010) Doping in Sports U.S