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The Effects of Meningitis on the Brain

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The Effects of Meningitis on the Brain
The Effects of Bacterial Meningitis on the Brain

Abstract Meningitis is an infection of the subarachnoid space (located between the middle arachnid matter and the inner pia mater) of the meninges, which is the thin layer of tissues that line the brain and the spinal cord. Cerebrospinal fluid flows through the subarachnoid space and the meninges, providing cushion for the brain and the spinal cord, and filling the internal spaces within the brain. There are 2 main types of meningitis, including bacterial meningitis and viral meningitis. There are other forms of meningitis, including fungal and amoebic, but they are extremely rare. Bacterial meningitis, which is the less common form of the disease, is associated with serious and severe illness. There are many major intracranial effects of bacterial meningitis. The dangerous inflammation that is caused by bacterial meningitis can cause brain edema, brain damage and increased pressure within the brain, and therefore lead to learning disabilities, hearing loss, or even death without treatment for the specific type of bacteria. This inflammation can produce a wide range of symptoms, including fever, headache, or confusion and, in extreme cases, can cause brain damage, stroke, seizures, or even death. The purpose of this paper is to discuss the pathogenesis of bacterial meningitis.

The Effects of Bacterial Meningitis on the Brain Bacterial meningitis is a very serious disease that is fatal in between 5% and 40% of patients and is known to cause neurological sequelae in 30% of survivors (Leib & Tauber, 1999). Bacterial meningitis can be caused by a number of different bacteria, including the most common; meningococcal bacteria, Haemophilus influenza and streptococcal infection (Department of Health, 2010). Unlike viral meningitis, it can potentially kill an otherwise healthy young person within 1 day after the first symptoms appear. The illness and death that is associated with bacterial

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    References: Center for Disease Control and Prevention. (December 13, 2002). Morbidity & Mortality Weekly Report (Version 51(49);1109-1112) [Report]. 2002. November 29, 2012, CDC Web site: http:/ / www.cdc.gov/ mmwr/ preview/ mmwrhtml/ mm5149a1.htm Center for Disease Control and Prevention. (November 15, 2012). The CDC and Public Health Response to the 2012 Fungal Meningitis and Other Infections Outbreak [2012 Testimony for HELP]. Available November 21, 2012, from U.S. Senate Web site: http:/ / www.help.senate.gov/ imo/ media/ doc/ Bell.pdf Center for Medicaid and CHIP Services. (October 31, 2012). CMCS Informational Bulletin (Version Unknown) [Meningitis Outbreak: Interim Treatment Guidance]. Available November 9, 2012, from Department of Health & Human Services Web site: http:/ / www.medicaid.gov/ Federal-Policy-Guidance/ downloads/ CIB-10-31-12.pdf Food and Drug Administration. (November 15, 2012). Statement of Margaret A. Hamburg, M.D [Testimony before HELP]. Available November 21, 2012, from U.S. Senate Web site: http:/ / www.help.senate.gov/ imo/ media/ doc/ Hamburg3.pdf Mercy Mount. (n.d.). In unknown (Ed.), Mercy Mount Country Day School. Retrieved December 3, 2012, from Mercy Mount Web site: http:/ / www.mercymount.org/ Capital/ CapitalListofDonors.htm O 'Reilly, K. B. (2012, October 29). In AMA (Ed.), Meningitis outbreak tests physician trust in compounding pharmacies [Article]. Retrieved October 29, 2012, from AMA Web site: http:/ / www.ama-assn.org/ amednews/ 2012/ 10/ 29/ prl21029.htm Pegues, D. A. (2006). Improving and Enforcing Compounding Pharmacy Practices to Protect Patients. Oxford Journal, 43(7), 838-840. Retrieved November 21, 2012, from JSTOR: http:/ / www.jstor.org/ stable/ 4484978 Perfect, J. R., & Schell, W. A. (1996). The New Fungal Opportunists Are Coming. Clinical Infectious Disease, 22(2), S112-S118. Retrieved November 22, 2012, from JSTOR Web site: http:/ / www.jstor.org/ stable/ 4459452 Professional Risk Advisor. (n.d.). In Unknown (Ed.), Professional Risk Advisor. Retrieved December 3, 2012, from Professional Risk Advisor Web site: http:/ / www.professionalriskadvisor.com/ 0303-settlement.html Serrie, J.…

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