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Platelet-Rich Plasma: A Novel Bioengineering Concept
Palwinder Kaur, Puneet, Varun Dahiya1
Department of Prosthodontics, Swami Devi Dyal Dental College & Hospital, Barwala, Distt. Panchkula. Haryana
1
Department of Periodontics, D J Dental College, Modinagar.
Corresponding author: Dr. Palwinder Kaur, e-mail: soniya.bagri@gmail.com
Received 19 August 2010; Accepted 12 January 2011; Available online 4 May 2011
A promising biologic therapy, offering various applications in dentistry is the use of platelet rich- plasma (PRP). PRP has became an increasingly popular clinical tool as an alternative source of growth factors for several types of dental procedures. These growth factors are described as promoters of tissue repair mechanisms and remodelling. The application of PRP in dentistry include sinus grafting, periodontal soft and hard tissue surgical procedures, ridge augmentation, dental implant osseous-integration etc. The use of PRP represents a relatively new concept of biotechnology that is becoming inseparable part of tissue engineering and cellular therapy today. The purpose of this article is to update clinician’s knowledge about the preparation of PRP, its most efficacious means of application and reviews the current literature on this emerging treatment modality.
Introdcution
Enhancement of the regenerative process of human body by utilizing the patient’s own blood, is a unique concept to dentistry. Platelet- rich plasma (PRP) is coming up as a biological revolution in dental field. PRP represents a similarity to the natural healing process, with the application of multiple growth factors. Growth factors are the biologically active substances that are involved in tissue-repair mechanism such as chemotaxis, cell proliferation, angiogenesis, extracellular matrix deposition, and remodelling. Platelet- rich plasma (PRP) has been traditionally used as a
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