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The Mortality of Workers with Occupational Lead Exposure

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The Mortality of Workers with Occupational Lead Exposure
R esearch Report PP06214, version 3
June 2011

The mortality of workers with occupational lead exposure: A research proposal
John W Cherrie
Damien McElvenny
Martie van Tongeren

OUR IMPACT ON THE ENVIRONMENT
At IOM we seek to minimise our environmental impact. We produce thousands of reports every year and these consume a large quantity of paper. To minimise our impact on the environment, we prefer to only provide an electronic copy of reports, although we can provide a paper copy on request. If you have any additional requirements please let us know.

PP06214 - V3– The mortality of workers with occupational lead exposure:
A research proposal

CONTENTS
LAY SUMMARY

II

MAIN PROPOSAL

1

1

WHAT IS THE WORK WE WOULD LIKE TO DO?

1

1.1
1.2

Introduction
Specific Aims

1
1

2

WHY SHOULD THE WORK BE UNDERTAKEN?

2

3

WHO IS DOING OR HAS DONE SIMILAR WORK, AND HOW WILL
YOUR WORK ADD TO IT?

3

4

HOW DO YOU INTEND TO CARRY OUT THE WORK, AND WHY DO
YOU THINK THIS IS THE RIGHT APPROACH?

3

4.1
4.2
4.3
4.4
4.5
4.6
4.7
4.8

Introduction
The study database
Study power
Research governance
Tracing subjects
Exposure assessment
Data analysis
Limitations

3
3
4
5
6
6
8
8

5

WHAT RESOURCES WILL YOU NEED TO DO THE WORK, AND ARE
THESE RESOURCES AVAILABLE?

9

6

WHO WILL DO THE WORK, AND HOW MUCH TIME WILL EACH OF
THE PEOPLE INVOLVED DEVOTE TO IT?

9

7

HOW LONG WILL THE WORK TAKE?

10

8

HOW MUCH MONEY DO YOU NEED TO COMPLETE THE WORK?

10

9

WHEN DO YOU PLAN TO START?

10

10

REFERENCES

10

APPENDIX 1: A BRIEF REVIEW OF THE RISKS ASSOCIATED WITH LEAD
EXPOSURE

12

APPENDIX 1: A BRIEF REVIEW OF THE RISKS ASSOCIATED WITH LEAD
EXPOSURE

12

APPENDIX 2: INSTITUTE OF OCCUPATIONAL MEDICINE

21

APPENDIX 3: CVS

23

Page i of ii

PP06214 - V3– The mortality of workers with occupational lead exposure:
A research proposal

LAY



References: (Burns & Beaumont, 1989). These data are generally linked to a more extensive visit report containing details of the factory and processes where the measurements were

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