Botany
Katakataka is an erect, more or less branched, smooth, succulent herb, 0.4 to 1.4 meters in height. Leaves are simple or pinnately compound, with the leaflets elliptic, usually about 10 centimeters long, thick, succulent, and scalloped margins. Plantlets grow along the notches of the leaf margins which can develop while still attached to the plant or when detached, a fascinating characteristic that earns its name. Flowers are cylindric, and pendulous in a large, terminal panicle. Calyx is tubular, cylindric, inflated, brownish or purplish, 3.5 to 4 centimeters long. Corolla is tubular, about 5 centimeters long, inflated at the base, and then constricted, the exserted parts being reddish or purplish and the lobes tapering to a point. Fruit is a follicle with many seeds.
Distribution
- In open settled areas, thickets, dry second-growth forests, sometimes planted, and locally abundant.
- Prehistoric introduction from tropical Asia or Malaya.
- Also cultivated, flowering from December to March.
- Pantropic.
Constituents
• Phytochemical screenings have yielded alkaloids, triterpenes, glycosides, flavonoids, steroids, butadienolides, lipids, and organic acids.
• Yields arachidic acid, astragalin, behenic acid, beta amyrin, benzenoids, bersaldegenin, beta-sitosterol, bryophollenone, bryophollone, bryophyllin, caffeci acid, ferulic acid, quercetin, steroids, and taraxerol.
• Phytochemical evalutation of leaf extract yielded bryophyllum A, B and C, a potent cytotoxic bufadienolide orthoacetate.
• Bufadienolide has been reported to be poisonous with digitalis-toxicity type cardiac effects (slowing of heart rate, heart blocks and potentially fatal ventricular arryhthmias.
• Bryophillin A, a bufadienolide compound, has shown anti-tumor promoting activity.
• Leaves yield malic acid.
Properties
• Leaves considered astringent, antiseptic, hemostatic, refrigerant, emollient, counterirritant, mucilaginous,