Thesis: the Diuretic Activity of Fresh Balloonvine Leaves

The Diuretic Activity of the Fresh Balloonvine (Cardiospermum halicacabum Linn) Leaves Extract RESEARCHERS
Arapoc, Kevin Ross
Flores, Van Giovanni
Jondonero, Graselle Navarro, Charizze
Serafino, Cherry Lou

A Research Project Presented to the Science Department of South Philippine Adventist College (SPAC) as Partial Fulfillment of the Requirements for the course Science IV (Physics)

Mr. Ranzolin G. Bayeta
Adviser

South Philippine Adventist College
Camanchiles, Matanao, Davao del Sur

February 25, 2011

ABSTRACT This study was conducted to know the diuretic activity of the extract of the balloonvine (Cardiospermum halicacabum L.) leaves. In this study, three groups were used. These includes the positive control group (furosemide 20mg/2ml), experimental group (balloonvine leaves extract), and the control group (water treated). The fresh leaves of balloonvine were extracted by pounding the leaves and then squeezed using a clean cloth. The mice were also weighed to determine the allowable dosage according to its weight. After the preparation of the groups, 3 trials were conducted. In the first trial, furosemide (positive control) has the most volume of urine, followed by the balloonvine leaves extract (experimental group) and the control group, which is the water treated has the least volume of urine. The next two trials have the same results as of trial 1. This means that furosemide is still the best diuretic drug but balloonvine leaves extract can also be used as a substitute since it has excreted more volume of urine than of the water treated group (control group) but not as good as the furosemide do. The researchers recommend further studies using other parts of the plant and using higher concentration to prove whether balloonvine can be more effective if used in higher dosage and to have more investigation of the plant.

Acknowledgment

The researchers would like to express their sincere gratitude to those who helped them finished this project.
Their

Bibliography: (http://www.plantoftheweek.org/week256.shtml) date retrieved: October 1, 2010 (http://www.plantoftheweek.org/week256.shtml) date retrieved: October 1, 2010 (http://www.britannica.com/EBchecked/topic/50726/balloon-vine) date retrieved: October 1, 2010 (http://www.dpi.qld.gov.au/4790_7120.htm) date retrieved: October 1, 2010 (http://en.wikipedia.org/wiki/Diuretic) date retrieved: October 1, 2010 (http://www.wisegeek.com/what-are-diuretics.htm) date retrieved: October 1, 2010 (http://en.wikipedia.org/wiki/Urine) date retrieved: October 1, 2010 (http://www.medterms.com/script/main/art.asp?articlekey=9462) (http://en.wikipedia.org/wiki/Syringe) date retrieved: October 1, 2010 (http://www.drugs.com/furosemide.html#ixzz11NvpwUe9) date retrieved: October 1, 2010 (http://www.medicinenet.com/furosemide/article.htm) date retrieved: October 1, 2010 (http://www.steadyhealth.com/encyclopedia/Albino_mouse) date retrieved: October 1, 2010 (http://en.wikipedia.org/wiki/House_mouse) date retrieved: October 1, 2010 (http://en.wikipedia.org/wiki/Funnel) date retrieved: October 1, 2010 (http://www.merriam-webster.com/dictionary/extracting) date retrieved: October 1, 2010 (http://dictionary.reference.com/browse/saponins?&qsrc=) date retrieved: October 1, 2010 (http://dictionary.reference.com/browse/tannins) date retrieved: October 1, 2010 (http://www.herbs2000.com/h_menu/alkaloids.htm) date retrieved: October 1, 2010 (http://en.wikipedia.org/wiki/Flavonoid) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Proanthocyanidin) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Apigenin) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Phytosterol) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Glycoside) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Cardiac_glycoside) date retrieved: October 3, 2010 (http://www.essential-oil-recipes.com/essential-oil-properties.html) date retrieved: October 3, 2010 (http://www.essential-oil-recipes.com/essential-oil-properties.html) date retrieved: October 3, 2010 (http://en.wikipedia.org/wiki/Anti-inflammatory) date retrieved: October 3, 2010 (http://www.medterms.com/script/main/art.asp?articlekey=6520) date retrieved: October 4, 2010 (http://www.essential-oil-recipes.com/essential-oil-properties.html) date retrieved: October 4, 2010 (http://www.essential-oil-recipes.com/essential-oil-properties.html) date retrieved: October 4, 2010 (http://en.wikipedia.org/wiki/Laxative) date retrieved: October 4, 2010 (http://www.essential-oil-recipes.com/essential-oil-properties.html) date retrieved: October 4, 2010 (http://en.wikipedia.org/wiki/Stomachic) date retrieved: October 4, 2010 ATTACHMENTS LOGBOOK September 15, 2010 was the passing of proposals September 19, 2010 was the day we started to construct our chapter 1 and chapter 2. We finished it for almost 3 weeks. October 15, 2010 was the passing of chapter 1. The night before that day, we have done review and had corrections. October 22, was the passing of chapter 2. October 28, 2010, we went to University of Sothern Mindanao to consult my cousin, Mrs