Tutorial 1 Q

ENT 318 ARTIFICIAL ORGAN

TUTORIAL 1
1. What are the factors holding back the use of implantable artificial organs?
2. What are the advantages of using artificial organs in comparison to transplanted organs?
3. Define the terms given below :
i.
Preload ii. Afterload iii. Cardiac Output iv. Mean Arterial Pressure

v. vi. vii.

Ventricular compliance
Venous Return
SVR

4. Sketch a Pressure-Volume plot for left ventricle. In your sketch indicate :
-EDV and ESV
-All the cardiac cycle phases
5. During exercise, venous return alters preload, afterload and inotropy. Discuss their physiological of increment according to ESV and EDV.
6. Explain the reason for having a reduction in stroke volume when afterload increased.
7. State the Frank-Starling Mechanism. Discuss effect of heart failure on the Frank-Starling curve. 8. Sketch a pressure-volume relationship of the left ventricle showing the condition of systolic dysfunction and diastolic dysfunction.
9. With a help of a diagram, describe how VAD helps to restore the sufficiency of oxygenated blood circulation through the whole body.
10. Explain the characteristics of peristaltic (roller) pumps in life support devices?
11. Explain the characteristics of rotary pumps in life support devices?
12. Explain the advantages of rotary pump over pulsatile pump.
13. Explain the possibilities of using an implantable VAD without percutaneous lead.
14. With a help of a diagram, demonstrate how a centrifugal pump could be used as a VAD.
15. Discuss the considerations/requirements in designing VAD.

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