Ulcerative Colitis Disease
What is the most affective medicine between balsalazide, 6.75 g Sulfasalazine 3.0g to treat ulcerative colitis?
Introduction
Picture 1 http://gastrointestinalatlas.com/UlcerativeColitisPc3.jpgUlcerative colitis is becoming a common condition in the UK . It is estimated that there are ten new cases a year out of every 100,000 people. There are currently 100,000 people in England with ulcerative colitis. The condition normally appears between the ages of 15 and 30[1]. This figure is supposed to rise in the coming years. Doctors are becoming more baffled as they do not know what is the right effective drug for their patient’s treatment. The two main drugs that are being used at the moment is balsalazide and Sulfasalazine. Both drugs are classed under a treatment called 5-ASA. For this type of treatment these are the two main drugs used by all doctors. [6]
Ulcerative colitis is grouped under a name of a disease called Inflammatory Bowel disease. Inflammation has a literal meaning of “being set on fire”. Inflammation normally occurs when a tissue has been damaged or destroyed; it is like the body’s response to tell you something is wrong [2]. In other words Ulcerative colitis in which the large intestine, but not the small, becomes inflamed and ulcerated. In Ulcerative colitis it is only the inner lining of the bowel, and not it’s full thickness, which is affected. Ulcerative colitis may affect the rectum, when it is usually called ‘proctitis’, or it may affect the bowel from anus to the top left of the colon (splenic flexure). [6]
Where does ulcerative colitis occur? Ulcerative colitis occurs in the colon. It always involves the rectum. It should be continuous, but can also be confined to patches in the colon. Some patients just experience inflammation in the rectum, others have it in the rectum and the sigmoid colon. The patients who suffer badly from the disease, normally have inflammation throughout the colon.
Graph 1
Introduction
Picture 1 http://gastrointestinalatlas.com/UlcerativeColitisPc3.jpgUlcerative colitis is becoming a common condition in the UK . It is estimated that there are ten new cases a year out of every 100,000 people. There are currently 100,000 people in England with ulcerative colitis. The condition normally appears between the ages of 15 and 30[1]. This figure is supposed to rise in the coming years. Doctors are becoming more baffled as they do not know what is the right effective drug for their patient’s treatment. The two main drugs that are being used at the moment is balsalazide and Sulfasalazine. Both drugs are classed under a treatment called 5-ASA. For this type of treatment these are the two main drugs used by all doctors. [6]
Ulcerative colitis is grouped under a name of a disease called Inflammatory Bowel disease. Inflammation has a literal meaning of “being set on fire”. Inflammation normally occurs when a tissue has been damaged or destroyed; it is like the body’s response to tell you something is wrong [2]. In other words Ulcerative colitis in which the large intestine, but not the small, becomes inflamed and ulcerated. In Ulcerative colitis it is only the inner lining of the bowel, and not it’s full thickness, which is affected. Ulcerative colitis may affect the rectum, when it is usually called ‘proctitis’, or it may affect the bowel from anus to the top left of the colon (splenic flexure). [6]
Where does ulcerative colitis occur? Ulcerative colitis occurs in the colon. It always involves the rectum. It should be continuous, but can also be confined to patches in the colon. Some patients just experience inflammation in the rectum, others have it in the rectum and the sigmoid colon. The patients who suffer badly from the disease, normally have inflammation throughout the colon.
Graph 1