WHAT SHOULD I KNOW ABOUT… DNA STRUCTURE, DNA REPLICATION, Tx, Tl, MUTATIONS, CELL CYCLE, MITOSIS, MEIOSIS, MENDELIAN GENETICS
Review/Use the following:
Vocab lists, ISN Pages, Practice Questions, Lectures, Book Chapters 12, 9, 10
DNA STRUCTURE
1. What role did Rosalyn Franklin play in our understanding of DNA’s structure? She discovered the double-helix position of the DNA.
2. What role did James Watson & Francis Crick play in our understanding of DNA’s structure? They discovered the 3D structure.
3. What type of macromolecular is DNA? Nucleic acid
4. What are the monomers of DNA? Nucleotides
5. What is the structure of a nucleotide? Draw It. A nucleotide consists of a phosphate molecule, a deoxyribose sugar, and a base (adenine, cytosine, gaunine, and thymine).
6. Which nucleotides are used to build DNA? Adenine, cytocine, guanine, thymine.
7. Which are used to build RNA? Adenine, uracil, cytocine, guanine.
8. What is a purine? How many rings do purines have? Purines are natural substances found in all of the body's cells, and in virtually all foods.
9. What is a pyrimidine? How many rings do pyrimidines have? 2 rings.
10. How is DNA different from RNA (strands, sugars, base pairs, location)? RNA is a nucleic acid polymer consisting of nucleotide monomers.RNA nucleotides contain ribose rings and uracil unlike DNA which contains deoxyribose and thymine.
11. What is the structure of a DNA molecule? a. What forms the backbone of the DNA molecule? Sugar rings and phosphates b. What kind of bonds occur between the 3' OH of one nucleotide and the phosphate of the next? Glycosidic bond b. What forms the “steps of the ladder”? Guanine, Adenine, Cytosine, and Thymine. c. What kind of bonds hold the nitrogen bases together? Hydrogen d. What is meant by anti-parallel strands? The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other