Information by DNA and
RNA
(My name)
December 2014
GRT1 Biochemistry Task 1
DNA Replication at the Biochemical
Level
• A DNA (Deoxyribonucleic Acid) molecule is in comprised of two strands of nucleotides.
• When DNA replicates, the nucleotide strands are split and used as a template for a new strand.
– The original strand (template) is called the parent strand
– The replicated strands are called daughter strands.
– A complete daughter DNA strand contains one strand from the parent, and one strand that has been added as a match for the template.
• Because the daughter strands each contain one strand of the original DNA, this process is semi-conservative.
(Wolfe, 2000c)
Replication
(continued)
• There are four nucleotides …show more content…
(Wolfe, 2000a)
Role of mRNA
• Transcription begins within the nucleus of a cell when mRNA binds to a segment of DNA and produces a copy.
• This mRNA moves out of the nucleus and into the cytoplasm. • Once in the cytoplasm, the mRNA is able to become a part of the process of translation.
• Codons in single strands of mRNA join with anticodons of tRNA (transfer RNA) to form proteins. (Wolfe, 2000a)
Transcription
(DNA transcription, 2014)
Translation
anticodon
NOTE: This is the same mRNA that has just been through the
Transcription process in the nucleus
(DNA transcription, 2014)
Role of RNA Polymerase Inhibition in
Death Cap Mushroom
• Death Cap mushrooms (Amanita phalloides) contain the deadly toxin α-amanitin.
• This toxin affects RNA …show more content…
(n.d.). Retrieved from http://thinkwell.cachefly.net/Protected/expiretime=1417625440;badurl=aHR0cDovL3dndS50aGlua3dlbGwuY29t/1 0a697611531addee4c74c585af7eed8/content/animations/26/26.html
Hudon-MIller, S. (2013). Death cap mushroom. Retrieved from http://wgu.hosted.panopto.com/Panopto/Pages/Viewer.aspx?id=45c5aef2-370e-43eb-ad9c-40f073926331 Hudon-MIller, S. (2013). DNA replication. Retrieved from http://wgu.hosted.panopto.com/Panopto/Pages/Viewer.aspx?id=2c8cb82e-03f8-4524-aecd-c3d314612141 Santi, L., Maggioli, C., Mastroroberto, M., Tufoni, M., Napoli, l., & Caraceni, P. (2012). Acute liver failure caused by amanita phalloides poisoning. International Journal in Hepatology, 2012. Retrieved from http://dx.doi.org/10.1155/2012/487480 The poison diaries. (n.d.). Retrieved from http://thepoisondiaries.tumblr.com/post/19733813804/amanita-phalloidesaka-death-cap
Wolfe, George. (March 16, 2000a). Events at the replication fork: the lagging strand. Thinkwell Biology: Molecular
Genetics. Retrieved from
http://wgu.thinkwell.com/students/getResources.cfm?levelFourID=5869723&levelThreeID=1820605&levelTwoID=