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Why Are Membranes Impermeable To Most Substances

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Why Are Membranes Impermeable To Most Substances
Why are membranes impermeable to most substances?
Membranes are impermeable to most substances due to the amphipathic structure of the lipid bilayer. The phospholipids form a bilayer in which the outer portion of each molecule is composed of a hydrophilic polar head and a hydrophobic non polar tail. The non polar tail groups face each other, making the inside of the membrane non polar. Due to the negative charges in the cell such as O2 and CO2, non polar molecules can diffuse across the membrane. The hydrophobic tail repels large molecules, polar molecules, and charged ions from moving across the membrane. Embedded proteins help glucose, ions, and other chemicals across the barrier. How do proteins function to make membranes selectively

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