Why Is Kidney Failure Important

In the past, kidney functions and diseases have been known as the most important encumbrance1. In 1960 the first patient began treatment at the University of Washington Hospital.2 A study confirmed that polycystic kidney disease is the main cause of kidney failure.3 patient should know about the causes that lead to kidney failure, the stages of it, symptoms and risk factors to prevent infection or decrease the effect of this disease in the future. Kidney is the most important members in the body. They organize fluid and cleaning the body. One of the most famous diseases is kidney failure. Kidneys failure might occur when a human has lack of water in the body, and that because the low blood pressure.4 In addition, it occurs when kidney infected with
a severe infection or high blood pressure. Moreover, eating a lot of medication without consulting a doctor may cause to lose kidney function. Patients who have obesity have possibility to infected kidney stones which leads to kidney failure.5 If patients' exposure to lead they may loss kidney function gradually.6 Kidneys failure department to five stages before it happens.7 In the first stage there will be no change in kidney function.7 For the second stage kidney functions will be slightly decrease.7 While the third stage is moderate, the kidney only has reducing in glomerular filtration rate (GFR).7
However, kidney so far can work effectively.7 In the fourth stage the kidney refers to a significant decrease in glomerular filtration rate (GFR).7 Moreover, most kidney cells will be destroying and other will be necrotic completely.7 At this stage the patient can stop the disease by protect the remaining cells from further damage.7 The last stage kidney will lose its function completely and
(GFR) will be less than 15%.
7 Which make patients need to have dialysis or transplantation.8 Patients with kidney failure do not have symptoms at the first stage of disease. As soon as, kidney function become worse, the symptoms of kidney failure will clearly appear. Kidney failure patients will begin feeling tired and fatigue.9 ''This is because uremic toxins build up in the blood and renal anemia appears''.9 Moreover, some patients may suffer from nausea and vomiting, that will reduce the materials in the body.4 another symptom that will affect patients' health are losing appetite and too much of weight.4,9 Also, there will be a metallic taste in the mouth and trouble thinking clearly.9 When kidney fail to take out toxins from the body, toxins will gather as swelling in legs, ankles, feet, and around eyelids.9 In addition, patients might have skin problems like
itching and dry skin based on high phosphorus level and deposits of large molecular toxins.9 Furthermore, calcium could haul out from the bone because of osteoporosis.9 Moreover, cardiac arrhythmias and skeletal muscle weakness are important symptoms to know.4 Kidneys failure cause risk factors in the human body like physical illnesses and psychiatric Illness, that may affect their lives. Physical illnesses could be cardiovascular disease, diabetes, hypertension, and obesity.10 Some researchers argue the main cause to increase the disease and reached to the last stage are diabetes and hypertension.11 They found that patients may die or will immediately be in the last stage of kidneys failure.12 In addition, the last stage contain three types glomerulonephritis, tubulointerstitial and renal ischemia.4 In the other hand, psychiatric illness. Patients are more likely to depression and dementia more than drug addict.13 A study case notes that patients have a death wish, suicidal intention and other psychological symptoms.14 Similarly, psychiatric illness can influences survival in patients.15 So doctors should give patients a special care in the clinical assessment. To sum up, there are many causes lead to kidney failure. Patients with low (GFR) will develop kidneys failure. These patients have to know their stage immediately so they can avoid kidney damage. symptoms of kidney failure are the same, but may differ from parson to another. The risk factors of kidney failure could happen without warning.