Depending on the type of ectopic pregnancy, the patient treatment may include medical management with methotrexate, or surgery. Methotrexate is an established medical treatment for unruptured ectopic pregnancy and it is preferred over surgical therapy because it is less invasive and less expensive. The patients must be counseled about the possibility of treatment failure, and the associated side effects of methotrexate which include bone marrow suppression, elevated liver enzymes, rash, alopecia, stomatitis, nausea, and diarrhea. The patient should also be counseled on the time to resolution of the ectopic pregnancy which is three to seven weeks after methotrexate therapy. Follow-ups with methotrexate treatment require weekly and sometimes daily measurement of β-hCG until the levels become undetectable. If the levels fail to decline, the patient can be treated with a second course of methotrexate. Surgical intervention is required if ruptured ectopic pregnancy is suspected, or if β-hCG increases. The surgical procedures include salpingostomy and salpingectomy (Lozeau, & Potter,
Depending on the type of ectopic pregnancy, the patient treatment may include medical management with methotrexate, or surgery. Methotrexate is an established medical treatment for unruptured ectopic pregnancy and it is preferred over surgical therapy because it is less invasive and less expensive. The patients must be counseled about the possibility of treatment failure, and the associated side effects of methotrexate which include bone marrow suppression, elevated liver enzymes, rash, alopecia, stomatitis, nausea, and diarrhea. The patient should also be counseled on the time to resolution of the ectopic pregnancy which is three to seven weeks after methotrexate therapy. Follow-ups with methotrexate treatment require weekly and sometimes daily measurement of β-hCG until the levels become undetectable. If the levels fail to decline, the patient can be treated with a second course of methotrexate. Surgical intervention is required if ruptured ectopic pregnancy is suspected, or if β-hCG increases. The surgical procedures include salpingostomy and salpingectomy (Lozeau, & Potter,