At the beginning of the play, Macbeth and Lady Macbeth they respect each other and are on exactly the same wavelength, so close they can almost read each other's thoughts when they are apart.“...I feel now / The future in the instant.” (I, v) Having decided to murder Duncan, their relationship becomes even more intense, it's a passionate, obsessive, almost sexual excitement. As well there’s fear and terror involved in the relationship. “What cannot you and I perform upon / Th’ unguarded Duncan?” (I, vii)
After Duncan's murder, Lady Macbeth appears stunned by Macbeth's killing of the guards. Suddenly she feels that the situation is getting out of control and Macbeth is becoming more vicious. This is the first time we feel they are growing apart. “O, yet I do repent me of my fury, / That I did kill them.” (II, iii)
During the time between the coronation and the banquet the relationship becomes very distressed. Neither of them are sleeping. Guilt is overcoming the couple. Macbeth begins to plan and think alone and shuts out Lady Macbeth from his thoughts. “How now my lord! why do you keep alone...?” (III, ii)
By the banquet scene, Lady Macbeth realises she can’t do anything to help her husband. At the end, she and her husband, have grown apart, so they are no in a relationship anymore. He is determined to go back to the witches; we feel that Macbeth is no longer trusting his wife but instead in “You lack the season of all natures, sleep.” (III, iv) After the banquet there is a long period when all Lady Macbeth can do is watch as Macbeth continues