Week 2 Virtual Lab: The Cell Cycle and Cancer
Worksheet
1. In which phase of mitosis do each of the following occur:
a. Centromeres split and chromosomes move toward opposite sides of the cell occur during the anaphase.
b. Chromatin coils to form visible chromosomes occur in the prophase.
c. The nuclear membrane disappears occur in the prophase.
d. Sister chromatids line up in the center of the cell occur in the metaphase.
2. In which phases of mitosis are sister chromatids visible, and attached to each other at the centromere?
During the metaphase of mitosis, sister chromatids are visible and attach to each other at the centromere.
Table 1: Record your data for the number of cells in each stage of the cell cycle observed in normal tissues.
Tissue Type
# Cells in Interphase
# Cells in Prophase
# Cells in
Metaphase
# Cells in Anaphase
# Cells in
Telophase
Lung Tissue
Sample 1
19
1
0
0
0
Lung Tissue
Sample 2
19
0
0
1
0
Stomach Tissue
Sample 1
16
1
1
0
2
Stomach Tissue
Sample 2
18
0
1
0
1
Ovarian Tissue
Sample 1
17
0
1
2
0
Ovarian Tissue
Sample 2
19
0
0
1
0
Table 2: Record your data for the number of cells in each stage of the cell cycle observed in cancerous tissues (in order to get two samples you will need to reset the microscope image).
Tissue Type
# Cells in Interphase
# Cells in Prophase
# Cells in
Metaphase
# Cells in Anaphase
# Cells in
Telophase
Lung Tissue
Sample 1
15
1
3
0
1
Lung Tissue
Sample 2
16
0
2
1
1
Stomach Tissue
Sample 1
14
2
1
1
2
Stomach Tissue
Sample 2
13
2
2
2
1
Ovarian Tissue
Sample 1
11
2
2
3
2
Ovarian Tissue
Sample 2
12
2
1
2
3
Table 3: Use the data in Table 1 to calculate the Mitotic Index (average % cells