Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease for which there are currently no treatments that slow or halt its progression(1) The cardinal early features of the disease are movement disorders‚ including chorea and incoordination‚ and later on‚ dystonia‚rigidity‚ and bradykinesia become more prominent.Patients die usually between 15 and 25 years after development of the first symptoms.(2‚3‚4) Brains from patients with HD show neuronal degeneration‚most prominently in
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MENDEL`S PRINCIPLES OF GENETICS 1.0 INTRODUCTION: 1.1 BACKGROUND Gregor Mendel‚ who is now considered as founder of classical genetics‚ ( Elrod S. & Stansfield w‚2010)‚ conducted a series of experiments using garden pea plants‚ his aim was to find a way of explaining to his fellow scientists who believed the blending theory which had been proposed earlier by Wiseman‚ that heredity involved the interaction of discrete separable factors (now known as genes) After a statistical analysis of the
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Mendel on Patterns of Inheritance Mendel was the first to see that traits in each person were passed down‚ not just from the parents‚ but also from grandparents‚ great-grandparents‚ great-great-grandparents‚ etc. He also figured out that not every person is the same as his or her own parents. Some of these traits can come from other family members that are no longer living. Mendel is the first to also describe these traits as passages through the generations. There are at least three reasons
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cellular organization‚ growth‚ reproduction‚ homeostasis and heredity. These characteristics define the term life. Then what is inheritance? Inheritance is something you possess from your ancestor and carried along‚ it may be any asset‚ money or anything but when we connect with the life what we will take from our parental generation and give it to our successors is INHERITANCE IN LIFE. Life had amazing property of transformations. It could transmit information to the next generation. It reproduced
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Description Huntington disease is a hereditary disease that causes the degeneration of nerve cells in the brain. Huntington disease‚ or hereditary chorea‚ has an extensive impact on a person ’s functional abilities and usually results in movement‚ perceptive and psychiatric disorders (Walker‚ 2007). It is named after the American physician George Huntington‚ who provided one of the first descriptions of the disease in 1872 (Huntington‚ 1872). The disease causes nerve cells in the brain to die which
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Human Genetic Engineering The debate on whether human genetic engineering should be researched and used as the main alternative solution to disease have been going on since the creation of the "human genetic engineering" phenomenon. The ethical question is clear: should money be invested in human genetic engineering and should we research it at all‚ even if it is formally criticized by all monotheistic religions? The ethical principles in conflict are beneficence (people with fatal diseases could
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Huntington disease Name Institute Huntington Disease Introduction Shortage of information about Huntington disease (HD) and its non-clinical management inveigled me into a quest for journal articles about this comparatively rare illness. Having pored over scores of Journal of Clinical Nursing Issues‚ I stumbled across the article entitled “Exploring supportive care for individuals affected by Huntington disease
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Genetic Modify Organisms Genetic Engineering Today many scientist use “genetic engineering” a new technology that manipulates the genes of many plants‚ bacteria and animals. This organisms are called genetic modified organism (GMOs) because their genetic material (DNA) has been changed in a way that it doesn’t occur naturally‚ it alters the organism’s genetic material through adding‚ deleting or changing the segments in the DNA. This technology is also referred to as "biotechnology" or "recombinant
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MECH A NIS MS OF D IS EASE Review Article Mechanisms of Disease F R A N K L I N H . E P S T E I N ‚ M. D. ‚ Editor ION CHANNELS — BASIC SCIENCE AND CLINICAL DISEASE AND MICHAEL J. ACKERMAN‚ M.D.‚ PH.D.‚ DAVID E. CLAPHAM‚ M.D.‚ PH.D. I ON channels constitute a class of proteins that is ultimately responsible for generating and orchestrating the electrical signals passing through the thinking brain‚ the beating heart‚ and the contracting muscle. Using the methods of molecular biology
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Genetics Problems 1. Brown eyes are dominant over blue. What are the chances that the first child of a marriage of two hybrid (heterozygous) brown-eyed parents will be blue-eyed? What are the chances of the second child being blue-eyed? BB Bb Bb bb There is a 25% chance that the first child will be blue-eyed and a 75% chance the child will be brown-eyed. There is a 50% chance that the trait for brown eyes will overpower the recessive trait for blue eyes. 2.In humans‚ color-blindness
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