KPIs for Drug Discovery STRATEGIC IMPERATIVES • • Product Quality Benchmarking among the competitors CRITICAL SUCCESS FACTORS • • • Sustainable quality High Standards Optimal Pricing Strategy KEY PERFORMANCE INDICATORS • • • • • Pioneers in Quality and Standards • • Positive results of Quality
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DNA synthesis inhibitors Nucleic acid inhibitors are chemicals which inhibit the production of nucleic acids including both DNA and RNA. DNA and RNA inhibitors inhibit enzyme action in DNA replication in the same way as the topoisomerase inhibitors we discussed earlier. Topoisomerase inhibitors (1) (10) are chemicals which interfere with the enzymes that allow DNA strands to separate and to re-join‚ a process that is required for the division of bacteria and without which DNA cannot effectively
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and beneficial for a broad spectrum of science‚ engineering and healthcare majors. However‚ without some hands-on laboratory experience‚ this understanding is likely to be incomplete‚ if not deficient‚ because chemistry is mostly an experimental (empirical) science. This course would provide the actual lab experience that is useful or even essential for a natural scientist‚ an engineer or a clinician/pharmacist. Beyond majors in chemistry the target student audience can pursue a career in medicine
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TYPES OF MAGNETIC MATERIALS Paramagnetic materials have a small‚ positive susceptibility to magnetic fields. These materials are slightly attracted by a magnetic field and the material does not retain the magnetic properties when the external field is removed. Paramagnetic properties are due to the presence of some unpaired electrons‚ and from the realignment of the electron paths caused by the external magnetic field. Paramagnetic materials include magnesium‚ molybdenum‚ lithium‚ and tantalum
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Watson and Crick discovering DNA Watson and Cricks discovery of DNA was important for many reasons because DNA made it possible to use genetic screening to identify which patients have ‘faulty’ genes which will lead to genetic illness such as Alzheimer’s. Watson and Crick discovered the structure of DNA in 1953. A reason that it was important was because it has provided an explanation for diseases and conditions that the germ theory cannot explain‚ for instance‚ cancer. This was important because
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Composite Materials A composite is a combination of two or more materials bonded together to gain some overall necessary goods. Types of composite include: laminated materials fibre composites particle composites. A laminate contains thin pieces of material fused together. Common examples are plywood and car windscreens. Wood is durable when exposed to a ductile force equivalent to its grain‚ but if the strength is across the particle it splits simply. A windscreen is made in a parallel way; two
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procedure for extracting DNA‚ collecting DNA samples‚ and to observe the physical characteristics of DNA Background: The wild strawberry is a diploid because it only has two sets of chromosomes. While the grocery store kind is an octoploidy because it has eight sets of chromosomes. The reason we chose the grocery store strawberry is because we’d be able to extract more DNA. Ripe strawberries make enzymes which help break down the cell walls making it easier to extract the DNA. We will be using a solution
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There were many political and technological changes that prompted the world explorations and discovery of the new world. The Portuguese were the main contributors to the technological changes that lead to the discovery of the new world. However‚ the change of the political structure of Spain ultimately lead to the discovery. There were many technological changes that the Portuguese contributed. First of all they observed the way the Arab vessels were designed and then improved on them to make
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DNA replication mechanism is an integral and the most important part of cell division. It is a complicated mechanism that requires a lot of steps and different enzymes. Many scientists were trying to understand the mechanism of DNA replication and its role in the transfer of the hereditary information to the offsprings. DNA replication begins with a single origin of replication that starts off the process by creating a replication bubble. In many eukaryotic cells‚ the DNA strand will have more than
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Part I - Illumination Experiments (1924-27) These experiments were performed to find out the effect of different levels of illumination (lighting) on productivity of labour. The brightness of the light was increased and decreased to find out the effect on the productivity of the test group. Surprisingly‚ the productivity increased even when the level of illumination was decreased. It was concluded that factors other than light were also important. Part II - Relay Assembly Test Room Study (1927-1929)
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