utilizing the technique of thin-layer chromatography‚ or TLC. The active ingredients of Excedrin were caffeine‚ acetaminophen‚ and aspirin with Rf values of 0.11‚ 0.38‚ and 0.61‚ respectively. The lone active ingredient of Tylenol was acetaminophen with an Rf value of 0.39. The elution sequence obtained in the experiment is as follows: ibuprofen (least polar)‚ acetylsalicylic acid‚ acetaminophen‚ and caffeine (most polar). Purpose of Experiment: The objective of this experiment is to determine the
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experiment is to investigate the composition of a simulated pharmaceutical preparation Panacetin‚ a proposed type of pain-killer. Panacetin is typically made up of sucrose‚ aspirin‚ and acetaminophen‚ but the third component in this experiment is unknown. The unknown component is suspected to be a chemical relative of acetaminophen‚ either acetanilide or phenacetin. Using techniques such as extraction‚ evaporation‚ and filtration‚ the three components will be isolated based on their solubilities and acid-base
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Introduction Chromatography is a technique used to separate a mixture into its individual components. In this experiment‚ chromatography is done by using a thin layer chromatography (TLC) plate and filter paper. The word ‘chromatography’ itself means the separation of colours. However‚ nowadays‚ both coloured and colourless compound are used in chromatography by various methods. In chromatography‚ the separation process of mixture is mainly based upon the polarity and molecular weight of sample
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better. In the article‚ “Adolescent Drug-Related ER Visits and Suicide Attempts” say‚ “Acetaminophen products were the most commonly used substances involved in hospital ER visits by female adolescents attempting suicide” (4). In other words‚ acetaminophen is a common drug female use while tries to attempt suicide. Acetaminophen is a drug that relieves pain and reduces fever and many other things. If acetaminophen are prescribed by a doctor it should not have any danger towards it. The danger only
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Shields 2016). The most common side effects are sedation and constipation (Wilson‚ Shannon‚ Shields 2016). Oxycodone can have life-threatening side effects such as respiratory depression and hepatoxicity‚ which is seen if oxycodone is combined with acetaminophen (Wilson‚ Shannon‚ Shields 2016). Oxycodone can interact with alcohol and St. John’s wort to increase sedation (Wilson‚ Shannon‚ Shields 2016) and “use of enzyme inducers such as rifampicin‚ St John’s wort and carbamazepine should be avoided because
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case of type I diabetes mellitus‚ went through a break up and he had to work long hours to support himself. He was probably under a lot of psychological and emotional stress‚ suffering from ’tension headache’ and took an over dose of Panadol or acetaminophen with alcohol. According to food and drug agency (2009)‚ a combination of these can cause acute liver failure‚ something that needs to be worked on in this case. Jeremy is taking insulin aspart (NovoRapid) which is rapidly acting insulin and insulin
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analysis by having us do a TLC analysis of analgesics to figure out their main chemical components. Calculations: 1.) Rf = Distance spot traveled/ distance solvent traveled Results: Table 1: TLC Analysis Analgesic Drugs | Rf Value | Acetaminophen | 0.323 | Aspirin | 0.597 | Caffeine | 0.081 | Unknown 154 (Plate 1) | 0.081‚ 0.306‚ 0.597 | Ibuprofen | 0.698 | Salicyclamide | 0.587 | Unknown 154 (plate 2) | 0.079‚ 0.397‚ 0.587 | Discussion: The goal of this experiment was
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Tylenol Chemical Formula: C8H9NO2 Molecular Weight: 151.16 Macroscopic Appearance: Acetaminophen is a white‚ crystalline powder What Tylenol is? Tylenol is an anodyne used for relieving mild pain‚aches and assuaging fever.Acetaminophen basically belongs to a category of drugs known as analgesics (pain relievers) and antipyretics (fever reducers). What the chemists say? Some chemists hold the opinion that this medicine may only be utillized for cure of inflammation‚but their claim is somewhat
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Krista Jinks CH 211L Section F 10/27/14 I. Abstract: The objective of this experiment was to analyze analgesic tablets by TLC to determine what analgesics they contain. The analgesics that could be in the tablets included ibuprofen‚ acetaminophen‚ aspirin‚ and caffeine. Through the use of TLC‚ unknown substance #62 was found to be Bayer Aspirin because it only contained aspirin. II. Introduction: 1. Briefly describe the process of Thin Layer Chromatography. Make it clear in the discussion
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(Experiment #15) The purpose of this experiment is to determine the components of an unknown drug and identify it as one of six (6) commercial drugs by using thin-layer chromatography. I added approximately a quarter of a tablet of acetaminophen‚ aspirin‚ caffeine‚ ibuprofen‚ salicylamide‚ and the unknown (#19) to separate test tubes containing 2.5mL of dichloromethane. I noticed that my unknown was a coated tablet. Each test tube was swirled until the greatest amount of each solid was
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