Abstract: This experiment is to demonstrate the preparation of paracetamol and its properties. Reflux and filtration of 4-aminophenol and acetic anhydride formed the crude sample. Further analysis of dry white crystals were used to give quantitative measurements and a percentage yield of 46% was obtained. The overall conclusion is that the acetic anhydride reacted with the –NH2 group. Materials and Methods: 1. We weighed out (on a top-pan balance) 4-aminophenol (about 11.0g) in a weighing
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Synthesis of Acetanilide Reaction O NH2 + H3C C O O C CH3 O N C CH3 H + H3C O C OH Aniline Acetic anhydride Acetanilide Acetic acid Purpose: Acetanilide is a useful precursor to many pharmaceuticals such as acetaminophen and penicillin. Experimental Procedure. (Estimated time: 1.5 h.) Unless otherwise noted‚ all manipulations should be done in the chemical fume hood. Place 100 µL of aniline into a tared 10 X 75-mm test tube (standing in a small beaker or Erlenmeyer flask). Now add
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Purpose: To synthesize acetylsalicylic acid on a microscale basis. Equipment / Materials: |salicylic acid |filter paper | | |acetic anhydride |hot water | | |conc. phosphoric acid |ice
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point of the aspirin sample‚ which will in turn indicate the purity of the sample. The last is conducting a colorimetric analysis on the aspirin sample. The educational goals of this lab are to find the structural formulas for salicylic acid‚ acetic anhydride‚ and aspirin and to use these structural formulas to construct a reaction equation by describing the synthesis of aspirin. In addition‚ you have to be able to use your percent purity calculations to determine the percent yield of your synthesis
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ice bath and a fluted filter paper while others were tasked to weigh the filter papers in advance so that the experiment will flow smoothly. The formation of crude acetanilide was due to the acetylation of aniline and acetic anhydride. The recrystallizing solvent dissolved the acetic acetanilide and was heated in a water bath. Crystals started to form after cooling the solutions in an ice bath. Pure acetanilide was the product after the second crystrallization which was obtained by finally removing
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of Santo Tomas Manila‚ Philippines ABSTRACT This experiment involved three steps: synthesis of aspirin‚ isolation and purification‚ and the estimation of purity of the final product. The synthesis involved the reaction of salicylic acid and acetic anhydride in the presence of a catalyst‚ phosphoric acid‚ H3PO4. When the aspirin was prepared‚ it was isolated and filtered. The percentage yield of the synthesis was calculated to be 78.42%. The experimental melting point range of aspirin was determined
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Preparation of Acetylsalicylic Acid Abstract Acetylsalicylic acid was prepared using salicylic acid and acetic anhydride. As a result‚ a white‚ powdery substance was formed (0.1931g‚ percent yield 91.30%) and was defined by melting point (124.5 – 134.5°C) and observation of color change with ferric chloride. Introduction Acetylsalicylic acid (aspirin) is one of the most popular analgesic drugs on the market today. It also acts as an antipyretic and anti-inflammatory drug. Salicylic acid itself
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mucous membranes of the mouth and stomach.Then‚ in 1893 a chemist named Felix Hoffman synthesized acetylsalicylic acid. The purpose of this experiment is to synthesize aspirin from salicylic acid and acetic anhydride. To filter and air dry to find the actual
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Y1315 Lab supporting staffs: YK Au / Kan Chan/Arnold Demonstrators: Dr. Samuel Lee‚ Alston Lee‚ Fu Wai Chung‚ Guo Shuai‚ Yuen On Ying‚ Sep 16 Tue Acetylation of α-D-glucopyranose (Expt 1) Sep 23 Tue Cis-1‚2‚3‚6-tetrahydro-4‚5-dimethylphthalic anhydride (Diels-alder reaction) (Expt 2) Sep 30 Tue Photochemical Reaction and Acid-catalyzed Rearrangement: Cycloaddition reactions (Expt.3‚ Part A) and Michael Addition (Expt 4‚ part A) Oct 7 Tue Michael Addition (Expt 4‚ part B) Oct 14 Tue Photochemical
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CHOONG SHING YI CHOONG SHING YI Preparation and Recrystallization of Aspirin Preparation and Recrystallization of Aspirin Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Date of the experiment: 9 May 2013 Date of submission: 23 May 2012 Synopsis 1. General Objective: To familiarize with the preparation of some simple organic compound and purify the compound by recrystallization. Specific Objective: The experiment is carried
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