Dose of drug administered ABSORPTION DISTRIBUTION Drug in tissues Drug in systemic circulation Pharmacokinetics Drug metabolized or excreted ELIMINATION Drug at site of action Pharmacologic effect Pharmacodynamics Toxicity Efficacy PHARMACOLOGY Pharmacodynamics Actions of drug on the body Specific to a drug/ class of drugs • Interaction with target sites (receptors/enzymes) • Effects at site of action • Dose-response relationship • Reduction in symptoms • Modification
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reaction for a chemical reaction 1. Activated Complex = temporary composite of atoms or molecules that will eventually form the products of the rxn. = highest point on diagram is potential energy of this composite = energy needed to form this composite = activation energy 2. Activation Energy - minimum amount of energy needed to form the Activated Complex and start the chemical reaction
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Coconut Industry The Philippines remains as the world’s leading supplier of traditional coconut products. The industry is also finding new products and uses for this the “Tree of Life”: coco peat‚ geotextiles‚ activated carbon and virgin coconut oil. Description The coconut industry is a dominant sector of Philippine agriculture: Of the 12 million hectare of farmlands‚ 3.25 M hectare is devoted to coconut 68 out of 79 provinces are coconut areas. Over 324M bearing and non-bearing trees 3.5M coconut
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dose in large amount is less effective than multiple doses in small amount (Pegg & Shahidi 2000). The carcinogenesis of N-nitrosamines requires several steps shown in figure 1. As N-nitrosamines are biochemically stable‚ they firstly need to be activated to form alpha-hydroxynitrosamines. This is done by cytochrome P450-dependent
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the engine‚ Sound produced under water is less hearable than it produced in atmosphere. This mainly because of small sprockets in water molecules‚ which lowers its amplitude thus‚ lowers the sound level. The emission can be controlled by using the activated charcoal layer and it is highly porous and posses extra free valences so it has high absorption capacity. So absorb the gases from the engine and release much less position to the environment. The noise and smoke level is considerable less than the
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Effector functions of antibodies Antibodies also known as immunoglobulins are secreted by plasma cells and B lymphocytes from the bone marrow and the lymphoid organs. The effector functions of antibodies are determined by the constant regions of the heavy chain. There are five different isotypes known in mammals to perform different roles and to direct a specific immune response for the antigen encountered. The binding of antigens to the variable regions will trigger the effector functions. Antibodies
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Hydrogen Producing Bacteria was incubated in a complete - mix digester with work volume 1.7 L‚ seeded with sludge obtained from the local sewage treatment plant. Each liter of feed medium was composed of the following : 7 g of glucose‚ 1 g NaHCO3 ‚ 500 mg of NH4Cl ‚ 250 mg KH2PO4 ‚ 250 mg K2HPO4 ‚ 320 mg of MgSO4 • 7H2O ‚ 50 mg of FeCl 3 ‚ NiSO4 32 mg ‚ 50 mg CaCl2‚ Na2BO7 7.2 mg H2O ‚ 14.4 mg (NH4) 6MO7O24 H2O ‚ 23 mg of ZnCl2 ‚ 21 mg CoCl2 H2O ‚ 10 mg CuCl2•2H2O and 30 mg of MnCl2•4H2O . The reaction
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chemical reaction occurs until the glass breaks‚ combining the chemicals together inside the tube. Cooling a glow stick slows the reaction a slightly and causes it to last longer‚ but the light is dimmer. This can be demonstrated by freezing an activated glow stick. When it is reheated‚ it will begin to glow again. However‚ if the chemical reaction has already occurred and the glow stick has already gone out‚ freezing the glow stick will not cause it to begin glowing again. A high quality glow stick
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cortisone can be considered an inactive metabolite of cortisol. However‚ 11-beta-steroid dehydrogenase can catalyze the reverse reaction as well‚ and‚ thus‚ cortisone is also the inactive precursor molecule of the active hormone cortisol. Cortisone is activated through hydrogenation of the 11-keto-group‚ and cortisol is‚ thus‚ sometimes referred to as hydrocortisone.[citation needed]Cortisone is one of several end-products of a process called steroidogenesis. This process starts with the synthesis of cholesterol
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Asian-American boys from the Boston area. They were recruited by local Chinese‚ Korean‚ and Japanese newspapers and summer programs at Chinatown. The participants were randomly assigned to one of three conditions: Asian identity activated‚ female/male identity activated‚ and no identity activated (control) or have not been defined
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