renal failure‚ and‚ rarely‚ death. Brown recluse venom‚ like many of the other brown spider venoms‚ is cytotoxic and hemolytic. It contains at least 8 components‚ including enzymes such as hyaluronidase‚ deoxyribonuclease‚ ribonuclease‚ alkaline phosphatase‚ and lipase. Sphingomyelinase D is thought to be the protein component responsible for most of the tissue destruction and hemolysis caused by brown recluse spider envenomation. The intense inflammatory response mediated by arachidonic acid
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during therapy. Monitor ANC. A rise may be seen 1-2 days after initiation of therapy‚ but therapy should not be discontiuned until ANC is greater than 10‚000/mm. May cause decreased platelets‚ and transient increases in uric acid‚ LDH‚ and alkaline phosphatase concentrations. Nsg Diagnosis: Risk for pain‚ Risk for infection‚ Risk for
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affecting the rate of reaction‚ PNPP (p-nitrophenyl phosphate) + H20 ? PNP (p-nitrophenol) + H3P04. This reaction is catalyzed by the enzyme phosphatase. Different environments produced different reaction rates as environmental factors affect the efficiency of phosphatase. This is because environmental factors can change the tertiary structure of phosphatase‚ which alters its active site‚ and thus changes its efficiency to catalyze the reaction. We measured the rate of reaction‚ by using a chromogenic
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Introduction • Bone tumor is neoplastic growth of tissue in bone‚ abnormal growth can benign or malignant. • Average five year survival in united states after being diagnosed with bone & joint cancer is 67%. CLASSIFICATION Tumor classified as primary tumors‚ which originate in bone derived cells & tissues.it may be neoplastic‚ developmental‚ traumatic‚ infectious & inflammatory etiology. Secondary tumors originate in other sites & spread (metastasizes) to skeleton. Carcinomas of prostate‚
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CANCER Cancer is not a single disease with a single disease with a single cause; rather‚ it is a group of distinct diseases with different causes‚ manifestations‚ treatments‚ and prognoses. Cancer‚ nursing practice covers all age groups and nursing specialties and is carried out in a variety of heath care settings‚ including the home‚ community‚ acute care institutions‚ outpatient centers‚ rehabilitation and goals of cancer nursing‚ also called oncology nursing‚ are diverse and complex as those
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HPLC detection and quantification of polyphenolic compounds Detection and quantification of selected phenolic compounds in the ethanol extract were determined by HPLC-DAD analysis as described by Ismet et al. [13] with some modifications. It was carried out on a Dionex UltiMate 3000 system equipped with quaternary rapid separation pump (LPG-3400RS) and photodiode array detector (DAD-3000RS). Separation was performed using Acclaim® C18 (5µm) Dionex column (4.6 x 250 mm) at 30 ºC with a flow rate of
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Jaundice (also known as icterus;[1] from the Greek word ίκτερος‚ attributive adjective: icteric) is a yellowish pigmentation of the skin‚ the conjunctival membranes over the sclerae (whites of the eyes)‚ and other mucous membranes caused by hyperbilirubinemia (increased levels of bilirubin in the blood).[2] This hyperbilirubinemia subsequently causes increased levels of bilirubin in the extracellular fluid. Concentration of bilirubin in blood plasma is normally below 1.2 mg/dL (50µmol/L) leads to
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Clinical Chemistry When people consider their careers in the health care field‚ most of them would think about being a physician‚ a nurse or a surgeon. Individuals with interest in the health care field are not aware of clinical laboratory science. I am one of those individuals who don’t know much about clinical laboratory science before. After taking the class “Introduction to Clinical Laboratory Science”‚ I start to realize that clinical laboratory scientists are just like other health care members
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the significance of ZnCl2 to acid phosphatase. ZnCl2 is dissociates into Zn2+ ions. Zn2+ ions are cofactors of acid phosphatase. The catalytic activity of the enzyme can enhances Zn2+ binding. Some enzymes are catalytically active without a requirement for additional ions or molecules. In others‚ activity depends on the presence of a non-protein cofactor. Cofactors fall into two major groups; they are either metal ions or organic compounds. Acid phosphatase uses Zn2+ ions as cofactors. Tightly
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in the haematological and serum electrolytes profile. While higher values were obtained in animals fed 20% inclusion of the test ingredient for globulin (32.00 g/L)‚ total cholesterol (3.00 mmol/L)‚ high density lipoproteins (1.00 mmol/L)‚ alkaline phosphatase (3.50 U/L)‚ alanine amino transferase (8.00 U/L) and aspartate amino transferase (10.00 U/L). It is concluded that there is no adverse effects of the yam peels diet on the experimental animals across all dietary treatments. It is however recommended
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