overlaid on the ATP-binding sites (5 Å) of Msm GyrB (orange‚ PDB code 4b6c17) and Spn ParE (magenta‚ PDB code 4mbc). The ligands from the 4b6c and 4mbc are removed for improved clarity. The ATP-binding sites of Mtb and Msm GyrB and Spn ParE are quite similar. (b) X-ray cocrystal structure showing key binding interactions of compounds 11 (green‚ PDB code 4mbc) and 20 (cyan‚ PDB code 4mb9) with selected Spn ParE ATP-binding-site residues. HB interactions between protein residues and associated water
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Claudine S. Lingat BSIT Prof. Marc Voltaire A. Padilla Thursday 10:00A-1:00PM Janet’s Pares House Corporation Chapter I: Problem Definition The Janet’s Pares House Restaurant is an establishment which prepares and serves food and drink to customers in return for money‚ paid before the meal. It is located near at RP Novaliches Q.C metro manila‚ there are (3) three branches (1) one in RP Novaliches and (2) two in Novaliches Bayan. Similar to other business they also encounter some problems
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injuries and comorbidities. By depth Currently‚ burns are described according to the depth of injury to the dermis and are loosely classified into first‚ second‚ third ‚ and fourth degrees. This system was devised by the French barber-surgeon Ambroise Paré and remains in use today.[7] It is often difficult to accurately determine the depth of a burn. This is especially so in the case of second degree burns‚ which can continue to evolve over time. As such‚ a second-degree partial-thickness burn can
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Amber Green English 102 03/15/2014 First Draft Advertisement Advertising is a very interesting topic because there are different ways that you can look at it. Advertising is a set of communications or activities used to influence and persuade consumers to adopt products and services. First‚ let me start off by defining advertising. The transfer of advertising attempts to transfer people’s feelings about one topic or product to another topic or product. When looking at advertising‚ try to
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KUSHTET NË TË CILAT U REALIZUA REVOLUCIONI BORGJEZ ANGLEZ. PREMISAT Anglia ishte e para nga monarkitë evropiane‚ e cila në kushtet e një refomimi të gjithëanshëm kaloi gradualisht nga absolutizmi mbretëror‚ i mbështetur me forcë nga katolicizmi‚ në bashkëqeverisjen e vendit mes Parlamentit dhe mbretit‚ një zbatim i plotë i koncepteve humaniste të bartura dhe tek reformacioni protestant. Megjithatë një kalim i tillë e kishte origjinën në ngjarje‚ të cilat u zhvilluan në një periudhë më të largët
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passengers comprised of 85 adults‚ 7 children and 4 infants. The aircraft disappeared from radar while cruising at 35‚000 feet. Following an extensive land‚ air‚ and sea search‚ wreckage was found in the water and on the shore along the coast near Pare-Pare‚ Sulawesi 9 days after the aircraft disappeared. Locator beacon signals from the flight recorders were heard on 21 January 2007 and their positions logged. The search was suspended when it was determined that the wreckage was located in the ocean
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he had raised enough money to travel to Europe where he could study and learn the effective and proven methods of educating deaf children. He traveled around England with little success at first‚ until he went to London‚ where he met Abbe Roche Ambroise Sicard‚ who was the head of the National Institute for the Deaf and Mutes in Paris. Sicard‚ at the time‚ was in London to present his theories about deaf education and to show his successful teaching methods of combining Old French Sign Language
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While listening to a radio station dedicated to classical music‚ my grandpa heard about a concert starring Kirk Muspratt and the New Philharmonic orchestra. He had been a long-time supporter and contributor to the orchestra and loved the conductor‚ so he wanted me to share his experiences as well. The New Philharmonic really is not the newest orchestra; it was founded 40 years ago with only 29 musicians who practiced in worn-down buildings. Originally founded to be a chamber group‚ the NP eventually
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become more of a Presidential figure in Parliament. Recent prime ministers that have been referred to as presidential include Margaret Thatcher‚ Tony Blair and Harold Wilson. Prime Ministers are supposed to be ‘First Among Equals’ (Primus Inter Pares)‚ however recent Prime Ministerial actions have got people questioning whether or not the Prime Minister has more power and is becoming a Presidential figure. The idea that
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Josephine Collins Performance Management & the Employee Appraisal Process Human Resource Week 7 &8 Mr. Ambroise Everest College of Dallas September 5‚ 2013 Performance Management is the process of creating a work environment in which people can perform to the best of their abilities in order to meet company goals. It is an entire work system that emanates from a company’s goals. The expectation of the company as follow are (1) The essential job functions the employee is expected to do
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