Gene therapy is an experimental treatment‚ which is used to replace mutated‚ improperly functioning genes with regular DNA. There are several gene therapy methods‚ most of which involve using a vector to transport the corrected gene into targeted cells. Retroviruses‚ adenoviruses‚ adeno associated viruses and liposomes are commonly used as vectors. Naked DNA (DNA without a vector) has also been used in gene therapy. Recently‚ gene therapy has been used as a treatment for deadly genetic conditions
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Testicular cancer involves the malignant transformation of normal gonocytes into germ cell tumours. It is the most common malignancy amongst men aged 15-35 years‚ and has a current cure rate of 90%‚ however incidence amongst Caucasian males is steadily rising.1 There are three main types: teratoma‚ usually neonates and children; seminoma/nonseminoma‚ occurs in men >15 years old; and spermatocytic seminoma which occurs in men >50 years old. Seminoma/nonseminoma are the most common‚ and only malignant
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NORMAL LEVEL-TWO ULTRASOUND SCAN Ultrasound examination during should include a systematic evaluation of fetal anatomy. Apart from anencephaly‚ the fetal organs cannot be accurately measured before 17-18 weeks of gestation. After 30-35 weeks‚ evaluation becomes increasingly difficult. Hence level-two ultrasound scan is done at 18 to 20 weeks of gestation. CLASSIFICATION OF FETAL SONOGRAPHIC EXAMINATIONS 1. First-Trimester Ultrasound 2. Standard Second- or Third-Trimester Ultrasound
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Biology Mitosis and Meiosis Study Guide Videos if you want/need them. https://www.youtube.com/watch?v=L0kenzoeOM https://www.youtube.com/watch?v=qCLmR9YY7o Maybe helpful sites? http://www.cellsalive.com/mitosis.htm http://www.cellsalive.com/cell_cycle.htm 1. Diagram and label a chromosome. 2. Describe the structure of a nucleosome. What is the role of the nucleosome in supercoiling AND in the regulation of transcription (You will have to check Campbell Ch
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About 1000 cycles have involved single gene mutational analysis.1 Mutational analysis requires additional skills beyond karyotyping for aneuploidies‚ including the ability to conduct the mutliplex polymerase chain reaction (PCR) of the gene of interest and related markers. Several new indications for PGD single gene mutational analysis have recently been reported. New uses include PGD
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Unit 2. Chapters 9-16. Cell Processes 1. Cellular Respiration‚ Photosynthesis‚ Cell Cycle‚ Mitosis‚ Meiosis‚ & Genetics. Note A: All work must be hand-written‚ including charts & diagrams. Note B: each answer requires more than one sentence & use diagrams whenever possible; failure to use diagrams will result in less points. Chapter 9 Outline 1) Principles of Energy Conservation a) Cellular respiration and fermentation are catabolic(energy – yielding) pathways b) Cells must recycle the ATP
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Acid Maltase Deficiency: It is an autosomal recessive disorder‚ in which the defect is in the gene for the acid maltase enzyme‚ which leads to accumulation of glycogen stored in muscles. Glycogen build up‚ weakens the muscles of a patient suffering from this disorder. This may affect respiratory muscles resulting in respiratory failure. It is also known as the Pompe Disease. Although‚ in childhood and adolescence the symptoms show slow progress and are less severe‚ infantile forms cause death within
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CHAPTER 14 1. Norm of reaction: the phenotypic range that a genotype is associated with due to environmental influences. 2. Multifactorial: characters that have many factors‚ both genetic and environmental‚ collectively influence phenotype. 3. Pleiotropy: when a gene controls multiple phenotypic effects 4. Epistasis: When a gene at one locus alters the phenotypic expression of a gene at a second locus 5. Carrier: a person who is heterozygous for a recessive disease and therefore
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_____ Please see me if you have any questions 1. Which of the following is NOT a common consequence of mutations that eliminate cell-cycle checkpoints? A. polyploidy B. increased chromosomal translocations C. increased DNA damage D. aneuploidy E. Increased apoptosis 2. Attenuation is fine tuning of gene regulation of operons for enzymes associated with anabolic (chemical building) pathways‚ such as the Trp operon for tryptophan synthesis. Which of the following is NOT true about
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