Myasthenia gravis Overview: Myasthenia Gravis is an autoimmune disorder of the post-synaptic neuromuscular junction whose pathogenesis consists in an attack on antibody-mediated At the acetylcholine receptor site on the postsynaptic membrane of the neuromuscular junction. Causes: Characteristics of the disease are muscle weakness and fatigue. The pattern of symptoms is typically fluctuating; it is more pronounced at night and improves with rest. Initial symptoms include: ptosis‚ diplopia or blurred
Premium Neurology Nervous system Neuron
Case Study A 17-year-old female with systemic lupus A 17-year-old female was admitted with a month long history of involuntary movement bilaterally in hand and legs. The patient stated that the movement started one month ago. And she had occasionally involuntary movement of her mouth. The symptoms were mild in the beginning and gradually increased. The patient had dyskinesia around her mouth and thoracic and occasionally choreathetoid movement in bilateral upper extremity. She said she had similar
Premium
Cells come from pre-existing cells via division Cells of all organisms fundamentally similar in structure‚ function‚ and metabolic functions Contain hereditary information passed down during cell division A cell’s volume increases faster than it’s surface area Less surface area = less are for nutrient/waste diffusion Solves via: Dividing‚ getting thinner‚ form microvilli‚ store nutrients (Microvilli – within small intestine) Cells are highly organized‚ 3 basic parts Plasma membrane Selective
Premium Immune system
group of chemicals called lymphokines. Some lymphokines kill the pathogens directly‚ others stimulate lymphocytes to become active and help increase the inflammation so that there are more macrophages. Helper T-cells co-operate with B-cells in the antibody production. They also activate macrophages and promote inflammation. Memory cells remain even after the pathogens have been killed to stop
Premium Immune system
Introduction to IMMUNOLOGY COURSE • Subject Agenda* Theoretical part (Lecture): 14.01----18.03----22.04.2013 Practical part (Labwork) • Study Materials: Textbook (David Male and Ivan Roitt-2006-DIR; Abul Abbas-2007AA)‚ Clips and Internet search • Classconversation@gmail.com. Pass: btiu12345 • Evaluation - Midterm Exam‚ Final Exam‚ Labwork - Assignment (Home-work‚ Topic-oriented-In-class discussion‚ Readand-Present Practice) Contact me at: R501‚ IU Building; or via email: ntthoai@hcmiu.edu
Premium Immune system
the frequency of thyroid antibodies and ATD is similar to that in classical T1DM. This findings suggests that T1DM co-morbidities may be common in clinical T2DM patients who have B-cell autoimmunity. Despite their obesity‚ youth with insulin requiring diabetes should be screened for thyroid and possible other T1DM associated autoimmune
Premium Research Scientific method Quantitative research
First‚ proteins are extracted from the tissue and loaded into a gel matrix. The matrix will separate the proteins according to size using an electric current. Proteins that are separated after are blotted from the gel and onto a paper membrane. An antibody is then added to the membrane paper and causes a colored reaction. Following the reaction‚ the results help detect and quantify a single protein among hundreds of other proteins in the sample. Western blotting is used during this procedure to test
Premium Molecular biology Protein Gel electrophoresis
from the immune system could identify organisms that invade the body; such as bacteria‚ and viruses. The antibodies are able to set off a complex chain of events designed to kill these foreign invaders. He found a way to create antibodies so strong they would allow their host to maintain the ultimate perfection for an indefinite amount of time. He had experimented trying to kill the new antibodies to test his theory‚ and found they were undying‚ --- they could not be destroyed. He kept injecting the
Premium Human Human body Immune system
2.2 Immunoprecipitation Different protocols were compared so as to choose the one which is compatible with the characteristics of the particular protein of interest [29]. A suitable amount of nuclear extracts was diluted with 100 microliters of chilled PBS‚ 0.1% Triton 100 (to this mixture‚ the following was added to make a final concentration of 1:1000: 0.2 mM PMSF‚ 0.5 mM DTT and 15 (microgram/ microliter). It was made sure that the final concentration of nuclear extract was 0.5-1.0(microgram/
Premium Protein DNA Solubility
The Immune System: Immune System Overview 1. Name the two major functions of the immune system: • __ To destroy disease-causing organisms_____________ • _______ To detect and kill abnormal cells such as cancerous cells________________ 2. Pathogens are classified according to their size and where they are located in the body. List the five types of pathogens from largest to smallest: • _____ Parasitic worms_____ • ________Fungi________________ • _____Protozoa_____________________ • ____Bacteria______________________
Premium Immune system