. Introduction A. Background of the Study One of the more common occurrences in our daily life is sustaining wounds ranging from mild abrasions to deep lacerations. Wounds that are left untreated can result to infections and other complications‚ so proper remediation must be done immediately. For the past several years‚ there has been a lot of advancement in the field of medicine. The discovery of new drugs has played a big role in the improvement of our health care. But due to the prohibitive
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Infertility/ Subfertility • one year of unprotected intercourse with the same partner without conception. • 10-15 % of couples • Multifactorial infertility male tubal & peritoneal ovulatory cervical & other Homocysteine & Fertility Dr. S. Bhanu Rekha Assoc. Prof SVS Pioneers Dr .Vigneaud 1933 Dr .Kilmer Mc Cully 1968 What is Homocysteine ? Protein diet Digestion Metabolism Methionine Auto-oxidation Protein synthesis 2)Homocystine 1)Homocysteine HS-CH2-CH2-CH-COOH NH2 Homocysteine •
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Glioblastoma (GBM) and the relationship with cancer stem cells Cancer stem cells may originate from normal stem cells‚ progenitor cells or from differentiated cells that revert to a stem-like phenotype. Under certain pressures such as therapy induce pressure the cell stems will potentiate the production of new cells that can be inherently resistance to the treatment that would be used4 . Cancer stem cell is known to have the ability to self-renew and maintain the tumor. Laboratory research have shown
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Cow’s milk allergy (CMA) is one of the major causes of food hypersensitivity in children. The clinical features of CMA express as immediate symptoms‚ ranging from mild local reactions to life-threatening anaphylaxis.‚ which may involve the skin (eg‚ urticaria and eczema)‚ respiratory tract (eg‚ asthma and rhinoconjuctivitis)‚ gastrointestinal tract (eg‚ vomiting‚ diarrhea‚ and colic)‚ or systemic anaphylactic shock. Cow’s milk contains more than 25 different proteins that are among the best characterized
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matrix pH when generation polyphosphates groups or decreasing magnesium of matrix [113]. During ischemia reperfusion‚ surprisingly at the‚ MPTP is opened and Pi is elevated. There is calcium overloading thanks to ROS generation‚ thus necrosis and apoptosis happen
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Amajala et al Journal of Drug Delivery & Therapeutics; 2012‚ 2(4)‚ 85-89 85 Available online at http://jddtonline.info RESEARCH ARTICLE METHYLATION PROFILING OF TUMOR SUPPRESSOR GENES INVOLVED IN LUNG CANCER * Krishna Chaitanya Amajala‚ Vishwanath A‚ Kaladhar DSVGK and Bhaskar Reddy I Department of Bioinformatics & Biochemistry‚ GITAM Institute of Science‚ GITAM University‚ Visakhapatnam-530045‚ Andhra Pradesh‚ India *Corresponding author’s Mail: chy2ak@gmail.com Received
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medication blocks the conversion of testosterone to DHT resulting in lower intraprostatic levels of DHT. This process causes change in epithelial cell of the transition zone. This process leads to inhibition of prostatic growth‚ involution‚ and apoptosis. Eventually‚ prostate volume and progression of disease will be decreased. Thus‚ patients with larger prostates may achieve a greater benefit. However‚ maximal reduction in prostate volume requires 6 months of therapy. These medications include Finasteride
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Quinazolines are the class of chemical compounds that are pharmacologically important as therapeutic agents. They are utilized as drugs and employed in cancer chemotherapy. They act by various mechanisms. Some of them act by inhibiting antifolat thymidylate syntheses‚ while some other derivatives inhibit tubulin polymerization. They were also found to inhibit the epidermal growth factor receptor (EGFR) tyrosine kinase over expression through the inhibition of autophosphorylation of EGFR. Further
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Medicinal uses of Turmeric Root.Curcuma Root.: Uses supported by clinical data: The principal use of Rhizoma Curcumae Longae is for the treatment of acid‚ flatulent‚ or atonic dyspepsia. Uses described in pharmacopoeias and in traditional systems of medicine: Treatment of peptic ulcers‚ and pain and inflammation due to rheumatoid arthritis and of amenorrhoea‚ dysmenorrhoea‚ diarrhqea‚ epilepsy‚ pain‚ and skin diseases. Uses described in folk medicine‚ not supported by experimental
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the short arm of chromosome 16 or chromosome 4 respectively. Birth genes encodes for polycostin -1 and polycytin -2 ion channel‚ proteins necessary for the proper functioning of renal filtration. Improper functioning of renal filtration lead to apoptosis‚ increased fluid sections‚ disorganized surrounding extracellular fluid leading to cyst enlargement. When these cyst enlarges they begin to compress causing ischemia and the occlusion of normal tubules in the kidneys leading to progressive renal
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