Tumour suppressor genes normally function to uncontrolled proliferation of cells within the body. They do this through a variety of means‚ they might prevent inappropriate progression of the cell cycle‚ or drive already cancerous cells towards apoptosis‚ and others simply check for errors during replication increasing fidelity (Sherr‚ 2004). Mutant versions that are present in cancers have lost the function to perform any of these properly. In contrast to oncogenes‚ tumour suppressor cells generally
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Thomas D Extended Research Task “The health benefits of red wine have come to light in recent years. Hope is on the horizon‚ and it may be in your glass!” Despite a seemingly indulgent high saturated fat diet‚ the French have a substantially lower death rate from coronary disease than any other major country. This phenomenon had been named the French Paradox and it is suggested that their consumption red wine may account for this strange occurrence (Mark Gould‚ 12/03/2006). In recent years
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Gene Therapy for Renal Diseases and Transplantation Contributions to Nephrology Vol. 159 Series Editor Claudio Ronco Vicenza Gene Therapy for Renal Diseases and Transplantation Volume Editors Ariela Benigni Bergamo Giuseppe Remuzzi Bergamo 15 figures‚ 4 in color‚ and 6 tables‚ 2008 Basel · Freiburg · Paris · London · New York · Bangalore · Bangkok · Shanghai · Singapore · Tokyo · Sydney Contributions to Nephrology (Founded 1975 by Geoffrey M. Berlyne) Ariela Benigni
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Phytochemical march allowed qualitative determining of the main groups of chemical constituents present in Licania arborea leaves. Abundant amount of amino acids‚ phenolic compounds‚ triterpenoids and tannins‚ moderated presence of flavonoids and leucoantocianidines‚ and the absence of nafto- and antroquinones‚ cardiotonics and alkaloids was observed. The high content of phenolic compounds happens to be interesting as there is a high probability polar extract from the leaves of this plant have antioxidant
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Stainin g What is Cellular Staining? Cell staining is a technique that can be used to better visualize cells and cell components under a microscope. By using different stains‚ one can preferentially stain certain cell components‚ such as a nucleus or a cell wall‚ or the entire cell. Most stains can be used on fixed‚ or non-living cells‚ while only some can be used on living cells; some stains can be used on either living is or non-living What Cellularcells. Staining? The most basic reason that
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ROR1 Can Play a Role in Breast Cancer Cell Growth Datoya Brown Tissue Culture & Hybridoma Technology BTCH 440-01 Dr. Lawrence Flowers 27 November 2012 Introduction Receptor tyrosine kinases (RTKs) are known to be key regulators of normal cellular processes such as differentiation‚ migration‚ proliferation and survival‚ but they also have a critical role in the development and progression of many types of human cancers. Before the published work concerning ROR1 was available it was
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For the treatment of cancer most of the drugs currently available but they have limited therapeutic potential because they are very toxic‚ expensive‚ highly inappropriate action in treating cancer‚ or having so many side effects like granulocytopenia‚ agranulocytosis‚ lymphocytopenia‚ alopecia‚ carcinogenicity or secondary cancer especially leukaemias and hyperuricaemia etc. Curcumin is one such natural herbal medicine‚ derived from the extraction of dried rhizome of turmeric or Curcumin longa‚
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Introduction Pernicious anemia (PA) is a type of macrocytic normochromic anemia. It is a slow-developing disorder with the underlying cause of Vitamin B12 absorption and deficiency due to lack of intrinsic factor (IF). Vitamin B12 absorption is facilitated by IF‚ which binds B12 in the duodenum‚ forming the IF-vitamin-B12 complex‚ later recognized by receptors and absorbed in the jejunum (Anderson‚ et al.‚ 445). A consequence of vitamin B-12 deficiency is altered DNA replication and erythropoiesis
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studied to identify their proteomes and how development affects the proteome (Labbe et al.‚ 2008). Study of isolated mitochondria has great application in the pharmaceutical industry through the discovery that some mitochondrial proteins stimulate apoptosis in the cells (Wang‚ 2001). This research has aided in finding cure for cancer and Parkinson’s disease among many other diseases (Labbe et al.‚ 2008). Also‚ many drugs produced contain drug classes that can inhibit the function of mitochondria by
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Hindawi Publishing Corporation ISRN Infectious Diseases Volume 2013‚ Article ID 571646‚ 6 pages http://dx.doi.org/10.5402/2013/571646 Review Article Pathogenesis of Dengue Haemorrhagic Fever and Its Impact on Case Management Kolitha H. Sellahewa Department of Medicine‚ Melaka Manipal Medical College‚ Jalan Batu Hampar‚ Bukit Baru‚ 75150 Melaka‚ Malaysia Correspondence should be addressed to Kolitha H. Sellahewa; kolithah@gmail.com Received 5 September 2012; Accepted 30 September 2012 Academic
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