halogen group is targeted. Enzymes like oxygenases play a major role. The bonds like ester-‚ amide-‚ or ether bonds present in the compounds are first attacked leading to breaking down of compounds. In some cases the aliphatic chains and in aromatic compounds the aromatic components may be targeted. The site and mode of attack depends on the action of enzyme‚ its concentration and the favourable
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b-CD) cavity protons as well as roxatidine acetate hydrochloride aromatic ring protons revealed the formation of a RAH–b-CD inclusion complex. Detailed FTIR and NMR spectroscopic (1H NMR‚ COSY‚ NOESY‚ ROESY) studies have been done. The stoichiometry of the complex was determined to be 1:1‚ and the overall binding constant was also determined by Scott’s method. The NOESY spectrum confirmed the selective penetration of the aromatic ring of RAH into the b-CD cavity in comparison to that of the piperidine
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Pharmacophore development for identification of anti-lung cancer drugs Pharmacophore development for identification of anti-lung cancer drugs Sadia Abbasi a‚*‚ Shanila Emmanuel a‚ Muhammad Haseeba‚ Aftab Khalil a‚ Saima Kulsoom b‚ Hamid Rashid a‚ Raisa Bano a a b Department of Bioinformatics‚ Mohammad Ali Jinnah University‚ Islamabad‚ Pakistan Department of Chemistry‚ Quiad-e-Azam University‚ Pakistan Lung cancer is one particular type of cancer that is more deadly and common than
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Name: Professor`s name: Course number: Date: Metabolic Pathways of Drugs The principal site for drug metabolism in the human body is the liver organ. The process of metabolism usually inactivates drugs though some drug metabolites are pharmacologically in active status. Inactive substance which has a metabolite that is active is referred to as a prodrug. Drugs are metabolized
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2. Qualitative ORGANIC functional group tests in various homologous series | TEST FOR | TEST METHOD | OBSERVATIONS | TEST CHEMISTRY and comments | ALKENE or alkyne i.e. any non-aromatic unsaturated hydrocarbon with a double or triple carbon-carbon bond. | Bubble gas through‚ or add liquid to‚ a solution of bromine in hexane or water. | The orange/brown bromine rapidly decolourises‚ as a saturated colourless organic bromo-compound is formed. | R2C=CR2 + Br2 ==> BrR2C-CR2BrRCCR + 2Br2 ==> Br2RC-CRBr2R
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converted to the orange sodium salt known as the methyl orange. INTRODUCTION Para-nitrobenzeneazoresorcinol dye and methyl orange belong to a class of dyes known as “azo colors” which contain the azo group linked to two aromatic nuclei. The nature of the aromatic substituent’s on both sides of the azo group (-N=N-) controls the colors of the azo compound as well as the water- solubility of dyes and how well they bind to a particular fabric. In addition to the azo group‚ the dyes
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fatty acid with an 18-carbon chain and has the IUPAC name octadecanoic acid. It is a white waxy solid. Formula: C18H36O2 Boiling point: 376.1 °C Melting point: 69.6 °C BENZOIC ACID is a colorless crystalline solid and a simple aromatic carboxylic acid. The name is derived from gum benzoin‚ which was for a long time the only source for benzoic acid. Formula: C7H6O2 Boiling point: 249.2 °C Melting point: 120-122 °C SALICYLIC ACID is a monohydroxybenzoic acid‚ a type of phenolic
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Pat 1 Synthesis of 4-aryl-6-indolylpyridine-2-carbonitriles and evaluation of their biological activity Synthesis of 6-indolyl-4-aryl-3-cyanopyridine-2-one (1a-e) Employing the MCRs approach and microwave irradiation‚ an equimolar amounts of aromatic aldehyde‚ 3-acetylindole‚ ethyl cyanoacetate were reacted with excess of ammonium acetate in one-pot‚ reaction‚ under the microwave irradiation‚ afforded a novel series of 4-aryl-6-indolyl-nicotinonitrile-2-one derivatives 1a-e. Ethylene glycol was
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The results of the experiments carriedout for the degradation of fabric dyes from aqueous solution using Chara and Chara beads are discussed below.Various analytical techniques like UV-Vis‚ FTIR spectroscopy were used to confirm the decolorization as UV-Vis spectroscopy; FT-IR spectroscopy and toxicity bioassay were truly used [14]. Also‚ Fourier transform infrared spectroscopy (FT-IR) is widely used to confirm the product obtained after decolorization of dye degradation experiments [15]
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INTRODUCTION: We are aware to the luxury of fashion affects our daily lifestyle. That’s why we came up to an idea of making organic resources more useful by inventing a new fragrance that will assure you a new unique scent. Our main of resource is the organic pee urine which can be content on making new tone of perfume together with its essential and fragrance oils and experience some exotic and unusual aromas from other original and unique sources. We’ll prove to you that Science can create a mystery
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